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- W1566756845 endingPage "283" @default.
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- W1566756845 abstract "Folate is an essential B vitamin required for the maintenance of AdoMet-dependent methylation. The liver is responsible for many methylation reactions that are used for post-translational modification of proteins, methylation of DNA, and the synthesis of hormones, creatine, carnitine, and phosphatidylcholine. Conditions where methylation capacity is compromised, including folate deficiency, are associated with impaired phosphatidylcholine synthesis resulting in non-alcoholic fatty liver disease and steatohepatitis. In addition, folate intake and folate status have been associated with changes in the expression of genes involved in lipid metabolism, obesity, and metabolic syndrome. In this review, we provide insight on the relationship between folate and lipid metabolism, and an outlook for the future of lipid-related folate research. © 2013 BioFactors, 40(3):277–283, 2014" @default.
- W1566756845 created "2016-06-24" @default.
- W1566756845 creator A5038500014 @default.
- W1566756845 creator A5040232188 @default.
- W1566756845 creator A5057550813 @default.
- W1566756845 creator A5058635992 @default.
- W1566756845 date "2013-12-18" @default.
- W1566756845 modified "2023-10-06" @default.
- W1566756845 title "Novel insights on interactions between folate and lipid metabolism" @default.
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- W1566756845 doi "https://doi.org/10.1002/biof.1154" @default.
- W1566756845 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4153959" @default.
- W1566756845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24353111" @default.
- W1566756845 hasPublicationYear "2013" @default.
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