FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1566786267> ?p ?o ?g. }

• W1566786267 endingPage "5389" @default.
• W1566786267 startingPage "5382" @default.
• W1566786267 abstract "Abstract Class I alloreactive CTL populations have been defined as either CD8 dependent or CD8 independent, based upon their ability to kill target cells in the presence of Ab to CD8. The CD8-dependent population uses CD8 in a coreceptor role with the TCR, and mutations in the class I molecule that destroy the CD8 binding site abrogate CTL killing, even if the target cell expresses other allelic forms of class I molecules with an intact binding site for CD8. The CD8-independent population apparently does not require CD8, as Ab to CD8 has no effect on the ability of these cells to kill appropriate target cells. We have isolated a third population of CTL that is inhibited by the addition of CD8 Ab yet can kill target cells that express the alloantigenic molecule incapable of binding CD8, provided that the target cells also express non antigenic class I molecules that contain an intact binding site for CD8. We refer to these cells as CD8 bystander-dependent CTL. Many (10 of 12) of these CTL were able to kill H-2Kb-expressing transfectants of T2 cells, consistent with the idea that they recognize a peptide-independent determinant that may be expressed at a high density on the cell surface. These CD8 bystander-dependent CTL are only readily detectable in vitro when spleen cells from mice primed in vivo with a skin graft are used." @default.
• W1566786267 created "2016-06-24" @default.
• W1566786267 creator A5061694041 @default.
• W1566786267 creator A5075361145 @default.
• W1566786267 date "1998-06-01" @default.
• W1566786267 modified "2023-09-23" @default.
• W1566786267 title "Alloreactive T Cells That Do Not Require TCR and CD8 Coengagement Are Present in Naive Mice and Contribute to Graft Rejection" @default.
• W1566786267 cites W1482318554 @default.
• W1566786267 cites W1496291074 @default.
• W1566786267 cites W1519011807 @default.
• W1566786267 cites W1527191816 @default.
• W1566786267 cites W1533542807 @default.
• W1566786267 cites W1579770523 @default.
• W1566786267 cites W1964741818 @default.
• W1566786267 cites W1967264483 @default.
• W1566786267 cites W1975991970 @default.
• W1566786267 cites W1985402375 @default.
• W1566786267 cites W1987752224 @default.
• W1566786267 cites W1996017127 @default.
• W1566786267 cites W1997904737 @default.
• W1566786267 cites W2000734326 @default.
• W1566786267 cites W2001852133 @default.
• W1566786267 cites W2006629564 @default.
• W1566786267 cites W2015066743 @default.
• W1566786267 cites W2015294490 @default.
• W1566786267 cites W2020055566 @default.
• W1566786267 cites W2024441858 @default.
• W1566786267 cites W2025465431 @default.
• W1566786267 cites W2031482359 @default.
• W1566786267 cites W2037260212 @default.
• W1566786267 cites W2044009370 @default.
• W1566786267 cites W2044524705 @default.
• W1566786267 cites W2047674370 @default.
• W1566786267 cites W2049099772 @default.
• W1566786267 cites W2050784170 @default.
• W1566786267 cites W2052869090 @default.
• W1566786267 cites W2055271950 @default.
• W1566786267 cites W2064888792 @default.
• W1566786267 cites W2066234545 @default.
• W1566786267 cites W2067060947 @default.
• W1566786267 cites W2074737029 @default.
• W1566786267 cites W2077861376 @default.
• W1566786267 cites W2078547056 @default.
• W1566786267 cites W2080103171 @default.
• W1566786267 cites W2080627154 @default.
• W1566786267 cites W2082173837 @default.
• W1566786267 cites W2085450869 @default.
• W1566786267 cites W2098642868 @default.
• W1566786267 cites W2108777421 @default.
• W1566786267 cites W2111045071 @default.
• W1566786267 cites W2117582013 @default.
• W1566786267 cites W2129968545 @default.
• W1566786267 cites W2132785861 @default.
• W1566786267 cites W2148382506 @default.
• W1566786267 cites W2149810322 @default.
• W1566786267 cites W2164339006 @default.
• W1566786267 cites W2762980752 @default.
• W1566786267 cites W4238735599 @default.
• W1566786267 cites W4239724425 @default.
• W1566786267 cites W1602931281 @default.
• W1566786267 doi "https://doi.org/10.4049/jimmunol.160.11.5382" @default.
• W1566786267 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9605138" @default.
• W1566786267 hasPublicationYear "1998" @default.
• W1566786267 type Work @default.
• W1566786267 sameAs 1566786267 @default.
• W1566786267 citedByCount "1" @default.
• W1566786267 crossrefType "journal-article" @default.
• W1566786267 hasAuthorship W1566786267A5061694041 @default.
• W1566786267 hasAuthorship W1566786267A5075361145 @default.
• W1566786267 hasBestOaLocation W15667862671 @default.
• W1566786267 hasConcept C147483822 @default.
• W1566786267 hasConcept C147969180 @default.
• W1566786267 hasConcept C153911025 @default.
• W1566786267 hasConcept C154317977 @default.
• W1566786267 hasConcept C167672396 @default.
• W1566786267 hasConcept C195616568 @default.
• W1566786267 hasConcept C202751555 @default.
• W1566786267 hasConcept C203014093 @default.
• W1566786267 hasConcept C2908647359 @default.
• W1566786267 hasConcept C54355233 @default.
• W1566786267 hasConcept C71924100 @default.
• W1566786267 hasConcept C86803240 @default.
• W1566786267 hasConcept C95444343 @default.
• W1566786267 hasConcept C99454951 @default.
• W1566786267 hasConceptScore W1566786267C147483822 @default.
• W1566786267 hasConceptScore W1566786267C147969180 @default.
• W1566786267 hasConceptScore W1566786267C153911025 @default.
• W1566786267 hasConceptScore W1566786267C154317977 @default.
• W1566786267 hasConceptScore W1566786267C167672396 @default.
• W1566786267 hasConceptScore W1566786267C195616568 @default.
• W1566786267 hasConceptScore W1566786267C202751555 @default.
• W1566786267 hasConceptScore W1566786267C203014093 @default.
• W1566786267 hasConceptScore W1566786267C2908647359 @default.
• W1566786267 hasConceptScore W1566786267C54355233 @default.
• W1566786267 hasConceptScore W1566786267C71924100 @default.
• W1566786267 hasConceptScore W1566786267C86803240 @default.
• W1566786267 hasConceptScore W1566786267C95444343 @default.
• W1566786267 hasConceptScore W1566786267C99454951 @default.

• next