Matches in SemOpenAlex for { <https://semopenalex.org/work/W1566882017> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1566882017 endingPage "9" @default.
- W1566882017 startingPage "274" @default.
- W1566882017 abstract "Activity of the microsomal enzyme p -nitrophenylglucuronyltransferase was increased in several transplantable rat hepatomas (Morris 7787, 7316A, 7794A, and Reuber H35 and H139) when the activities were compared on a tissue protein basis with those of normal and host liver. Significant activity, comparable to that in liver, was found also in Morris 3924A and 3683 hepatomas and high- and low-catalase hepatomas. Ability to conjugate p -nitrophenol was measured with freshly prepared homogenates as well as homogenates and isolated microsomal fractions which had been activated with the nonionic detergent Triton X-100. The maximal velocity measured for microsomes indicated, in several well-differentiated hepatomas, an apparent increase in the number of enzymatic sites per unit of microsomal protein as compared with liver. Glucuronyltransferase activity of rat liver was induced to the level present in the well-differentiated hepatomas 45 hr after a single dose of 3-methylcholanthrene. β-Glucuronidase activity towards p -nitrophenyl-β-glucuronide, measured under conditions used to assay glucuronyltransferase activity, was low for both liver and hepatoma preparations and would not have had a determining effect on the relative glucuronyltransferase activities observed for hepatomas and livers. Tissue culture cells derived from Morris 7288C hepatoma were able to conjugate p -nitrophenol added to the medium, indicating that not only is glucuronyltransferase active in intact hepatoma cells but that the supporting systems ( i.e. , synthesis of uridine diphosphate glucuronic acid and cell transport) are functional also." @default.
- W1566882017 created "2016-06-24" @default.
- W1566882017 creator A5006537594 @default.
- W1566882017 creator A5044252463 @default.
- W1566882017 creator A5055333894 @default.
- W1566882017 creator A5081361079 @default.
- W1566882017 date "1970-02-01" @default.
- W1566882017 modified "2023-09-23" @default.
- W1566882017 title "Glucuronyltransferase activity in transplantable rat hepatomas." @default.
- W1566882017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4318835" @default.
- W1566882017 hasPublicationYear "1970" @default.
- W1566882017 type Work @default.
- W1566882017 sameAs 1566882017 @default.
- W1566882017 citedByCount "3" @default.
- W1566882017 crossrefType "journal-article" @default.
- W1566882017 hasAuthorship W1566882017A5006537594 @default.
- W1566882017 hasAuthorship W1566882017A5044252463 @default.
- W1566882017 hasAuthorship W1566882017A5055333894 @default.
- W1566882017 hasAuthorship W1566882017A5081361079 @default.
- W1566882017 hasConcept C100817775 @default.
- W1566882017 hasConcept C104317684 @default.
- W1566882017 hasConcept C126322002 @default.
- W1566882017 hasConcept C134018914 @default.
- W1566882017 hasConcept C134306372 @default.
- W1566882017 hasConcept C181199279 @default.
- W1566882017 hasConcept C185592680 @default.
- W1566882017 hasConcept C197336794 @default.
- W1566882017 hasConcept C198684833 @default.
- W1566882017 hasConcept C2776648616 @default.
- W1566882017 hasConcept C2778979269 @default.
- W1566882017 hasConcept C2779186261 @default.
- W1566882017 hasConcept C2779907587 @default.
- W1566882017 hasConcept C2781259782 @default.
- W1566882017 hasConcept C2781278898 @default.
- W1566882017 hasConcept C28212737 @default.
- W1566882017 hasConcept C33923547 @default.
- W1566882017 hasConcept C55493867 @default.
- W1566882017 hasConcept C62231903 @default.
- W1566882017 hasConcept C67705224 @default.
- W1566882017 hasConcept C71924100 @default.
- W1566882017 hasConcept C86803240 @default.
- W1566882017 hasConcept C87644729 @default.
- W1566882017 hasConceptScore W1566882017C100817775 @default.
- W1566882017 hasConceptScore W1566882017C104317684 @default.
- W1566882017 hasConceptScore W1566882017C126322002 @default.
- W1566882017 hasConceptScore W1566882017C134018914 @default.
- W1566882017 hasConceptScore W1566882017C134306372 @default.
- W1566882017 hasConceptScore W1566882017C181199279 @default.
- W1566882017 hasConceptScore W1566882017C185592680 @default.
- W1566882017 hasConceptScore W1566882017C197336794 @default.
- W1566882017 hasConceptScore W1566882017C198684833 @default.
- W1566882017 hasConceptScore W1566882017C2776648616 @default.
- W1566882017 hasConceptScore W1566882017C2778979269 @default.
- W1566882017 hasConceptScore W1566882017C2779186261 @default.
- W1566882017 hasConceptScore W1566882017C2779907587 @default.
- W1566882017 hasConceptScore W1566882017C2781259782 @default.
- W1566882017 hasConceptScore W1566882017C2781278898 @default.
- W1566882017 hasConceptScore W1566882017C28212737 @default.
- W1566882017 hasConceptScore W1566882017C33923547 @default.
- W1566882017 hasConceptScore W1566882017C55493867 @default.
- W1566882017 hasConceptScore W1566882017C62231903 @default.
- W1566882017 hasConceptScore W1566882017C67705224 @default.
- W1566882017 hasConceptScore W1566882017C71924100 @default.
- W1566882017 hasConceptScore W1566882017C86803240 @default.
- W1566882017 hasConceptScore W1566882017C87644729 @default.
- W1566882017 hasIssue "2" @default.
- W1566882017 hasLocation W15668820171 @default.
- W1566882017 hasOpenAccess W1566882017 @default.
- W1566882017 hasPrimaryLocation W15668820171 @default.
- W1566882017 hasRelatedWork W1966504330 @default.
- W1566882017 hasRelatedWork W1979139803 @default.
- W1566882017 hasRelatedWork W2030889776 @default.
- W1566882017 hasRelatedWork W2037631372 @default.
- W1566882017 hasRelatedWork W2040058909 @default.
- W1566882017 hasRelatedWork W2064362993 @default.
- W1566882017 hasRelatedWork W2070567609 @default.
- W1566882017 hasRelatedWork W2090960426 @default.
- W1566882017 hasRelatedWork W2132898409 @default.
- W1566882017 hasRelatedWork W2391409986 @default.
- W1566882017 hasVolume "30" @default.
- W1566882017 isParatext "false" @default.
- W1566882017 isRetracted "false" @default.
- W1566882017 magId "1566882017" @default.
- W1566882017 workType "article" @default.