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- W1566895900 abstract "Milk fat globule membrane (MFGM) is a protein-lipid biopolymer that originates from the apical surface of mammary epithelial cells and surrounds fat globules in milk. During milk synthesis, fat droplets originate in the endoplasmic reticulum and travel directly to the cell’s apical surface. As they travel from the epithelial cells into the alveolar lumen, they pass through the apical membrane and are encapsulated in the plasma membrane complete with the exterior glycocalyx resulting in discrete globules. These milk fat globules have a nonpolar lipid core composed primarily of triglycerides that is surrounded by the MFGM which contains both membrane polar lipids and glycoproteins. While MFGM is in all dairy products containing milk fat, it is especially enriched in churn buttermilk, a co product of butter production. When milk fat is churned, the membrane surrounding the fat globules is disrupted, and the free fat released from the globules coalesces. This process ultimately results in a solid fat phase, butter, and an aqueous phase, also known as churn buttermilk. This material, buttermilk, has a long history of anecdotal health-promoting associations, yet it does not currently generate any added value in the market place for delivering nutritional benefit. MFGM has recently been shown in lipidomic and proteomic characterizations to have an interesting carbohydrate, lipid and protein profile. The phospholipids and membrane glycoproteins found in MFGM likely interact extensively with the gut epithelia during digestion, both physically and biochemically. Moreover, MFGM has a relatively high concentration of sphingolipids, which in purified form have been demonstrated to be protective against colon cancer. The unique composition of MFGM has led to the idea that it may have remarkable nutraceutical properties, however, few studies have tested this hypothesis. Recent studies from our laboratory have demonstrated that dietary MFGM improves gut barrier function in cell and animal models and is protective against colon cancer in a rodent model. In this chapter we will discuss the isolation, composition, biochemical properties and intestinal health promoting effects of the biopolymer MFGM." @default.
- W1566895900 created "2016-06-24" @default.
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- W1566895900 date "2011-06-24" @default.
- W1566895900 modified "2023-10-05" @default.
- W1566895900 title "Nutraceutical Properties of Milk Fat Globular Membrane" @default.
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- W1566895900 cites W1546332065 @default.
- W1566895900 cites W1562457256 @default.
- W1566895900 cites W1775391605 @default.
- W1566895900 cites W1896313493 @default.
- W1566895900 cites W1909858398 @default.
- W1566895900 cites W1913889129 @default.
- W1566895900 cites W1947272852 @default.
- W1566895900 cites W1950694960 @default.
- W1566895900 cites W1963529212 @default.
- W1566895900 cites W1965169001 @default.
- W1566895900 cites W1965704337 @default.
- W1566895900 cites W1966110677 @default.
- W1566895900 cites W1968637776 @default.
- W1566895900 cites W1969320146 @default.
- W1566895900 cites W1970817078 @default.
- W1566895900 cites W1976368143 @default.
- W1566895900 cites W1977406542 @default.
- W1566895900 cites W1979603997 @default.
- W1566895900 cites W1981371644 @default.
- W1566895900 cites W1985825196 @default.
- W1566895900 cites W1987778486 @default.
- W1566895900 cites W1991757395 @default.
- W1566895900 cites W1999643642 @default.
- W1566895900 cites W2005287203 @default.
- W1566895900 cites W2005984678 @default.
- W1566895900 cites W2008037659 @default.
- W1566895900 cites W2010299876 @default.
- W1566895900 cites W2018619889 @default.
- W1566895900 cites W2020198704 @default.
- W1566895900 cites W2032458398 @default.
- W1566895900 cites W2032864333 @default.
- W1566895900 cites W2036443575 @default.
- W1566895900 cites W2036732296 @default.
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- W1566895900 cites W2059945363 @default.
- W1566895900 cites W2062555360 @default.
- W1566895900 cites W2065683366 @default.
- W1566895900 cites W2067491481 @default.
- W1566895900 cites W2073381536 @default.
- W1566895900 cites W2073415968 @default.
- W1566895900 cites W2073762912 @default.
- W1566895900 cites W2073996477 @default.
- W1566895900 cites W2077811409 @default.
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- W1566895900 cites W2086809297 @default.
- W1566895900 cites W2092284740 @default.
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- W1566895900 cites W2148356114 @default.
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- W1566895900 cites W2274316681 @default.
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- W1566895900 doi "https://doi.org/10.5772/16722" @default.
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