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- W1566953684 abstract "Purpose: Tumor histology, characterized by adenocarcinoma (AD) or squamous cell carcinoma (SQ), has been related to differences in smoking history and gender. The aim of this epidemiological study was to investigate specificity of tumor histology and the effect of tobacco smoking in non-small cell lung cancer (NSCLC) patients in Taiwan.Methods: Data was collected for 315 NSCLC patients treated at Chung Shan Medical University Hospital between 1998 and 2006. Logistic regression testing and Cox proportional hazard model were used to identify the determinates for specific histology and for cancer death among NSCLC patients, respectively.Results: Among the factors affecting tumor histology of AD, the adjusted odds ratio for nonsmokers was almost 10 times as high as that for smokers (p＜0.05), whereas the other factors, including age, gender and cancer stage, were not found to be significant. With regard to cancer death, multivariate Cox hazard models showed that cancer stage and age to be independent prognostic indicators.Conclusion: In Taiwan, smoking history was the major determinate of tumor histology of lung cancer but not gender. Cancer stage at diagnosis remains the most powerful indicator of prognosis in lung carcinoma." @default.
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- W1566953684 date "2008-06-01" @default.
- W1566953684 modified "2023-09-23" @default.
- W1566953684 title "Smoking History Associated with Specific Histology but not Predicting the Prognosis of Non-small Cell Lung Cancer: Results from Chung Shan Medical University Hospital" @default.
- W1566953684 doi "https://doi.org/10.30096/csmj.200806.0002" @default.
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