Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567147756> ?p ?o ?g. }
- W1567147756 endingPage "331" @default.
- W1567147756 startingPage "320" @default.
- W1567147756 abstract "We studied the effects of ethanolic leaf extract of Azadirachta indica (AIE) on hepatic microscopic anatomy and oxidative stress markers in diabetic rats. Seventy-five Wistar rats (8 weeks old) were randomly assigned to five treatment groups: control; diabetic; diabetic+AIE; AIE only; and diabetic+glibenclamide. Hyperglycemia was induced in fasted rats with streptozotocin. AIE was administered orally at 500 mg/kg bw/d and glibenclamide at 600 μg/kg bw/d for 50 days (50 d). Animals were sacrificed on treatment days 7, 21 and 50. The liver was stained with PAS. Hepatic markers of oxidative stress were also estimated. At 50 d, histological study of the liver of diabetic rats showed swollen PAS+ hepatocytes, whose content was confirmed to be glycogen. On the contrary, hepatocytes of AIE-treated diabetic rats lacked glycogen. The major finding in these rats was exacerbated oxidative stress. Our findings in this model showed the beneficial effect of AIE in the amelioration of diabetic hepatic glycogenosis. Keywords: Diabetes, Azadirachta indica, hepatic glycogenosis, oxidative stress, liver" @default.
- W1567147756 created "2016-06-24" @default.
- W1567147756 creator A5001070695 @default.
- W1567147756 creator A5008216039 @default.
- W1567147756 creator A5030620823 @default.
- W1567147756 creator A5051701996 @default.
- W1567147756 creator A5054936054 @default.
- W1567147756 creator A5064901353 @default.
- W1567147756 date "2010-01-01" @default.
- W1567147756 modified "2023-09-23" @default.
- W1567147756 title "Azadirachta indica Leaf Extract Ameliorates Hyperglycemia and Hepatic Glycogenosis in Streptozotocin-induced Diabetic Wistar Rats" @default.
- W1567147756 cites W100277804 @default.
- W1567147756 cites W126978535 @default.
- W1567147756 cites W131211302 @default.
- W1567147756 cites W1529592271 @default.
- W1567147756 cites W1542458632 @default.
- W1567147756 cites W1957725278 @default.
- W1567147756 cites W1968638315 @default.
- W1567147756 cites W1984053870 @default.
- W1567147756 cites W1986928947 @default.
- W1567147756 cites W1989074935 @default.
- W1567147756 cites W2004953987 @default.
- W1567147756 cites W2008832041 @default.
- W1567147756 cites W2017208501 @default.
- W1567147756 cites W2022689643 @default.
- W1567147756 cites W2025565867 @default.
- W1567147756 cites W2025879003 @default.
- W1567147756 cites W2026651251 @default.
- W1567147756 cites W2028515800 @default.
- W1567147756 cites W2028900142 @default.
- W1567147756 cites W2032165809 @default.
- W1567147756 cites W2037565543 @default.
- W1567147756 cites W2039963918 @default.
- W1567147756 cites W2040427882 @default.
- W1567147756 cites W2044924822 @default.
- W1567147756 cites W2047504616 @default.
- W1567147756 cites W2062633726 @default.
- W1567147756 cites W2073819543 @default.
- W1567147756 cites W2075011306 @default.
- W1567147756 cites W2084346619 @default.
- W1567147756 cites W2099805775 @default.
- W1567147756 cites W2100271051 @default.
- W1567147756 cites W2100516241 @default.
- W1567147756 cites W2102768596 @default.
- W1567147756 cites W2105620133 @default.
- W1567147756 cites W2109620445 @default.
- W1567147756 cites W2115337518 @default.
- W1567147756 cites W2138228743 @default.
- W1567147756 cites W2143926978 @default.
- W1567147756 cites W2144677134 @default.
- W1567147756 cites W2165811356 @default.
- W1567147756 cites W2167121173 @default.
- W1567147756 cites W2238459434 @default.
- W1567147756 cites W2239503191 @default.
- W1567147756 cites W2274992324 @default.
- W1567147756 cites W2402244402 @default.
- W1567147756 cites W27186103 @default.
- W1567147756 cites W32180728 @default.
- W1567147756 hasPublicationYear "2010" @default.
- W1567147756 type Work @default.
- W1567147756 sameAs 1567147756 @default.
- W1567147756 citedByCount "2" @default.
- W1567147756 countsByYear W15671477562013 @default.
- W1567147756 countsByYear W15671477562015 @default.
- W1567147756 crossrefType "journal-article" @default.
- W1567147756 hasAuthorship W1567147756A5001070695 @default.
- W1567147756 hasAuthorship W1567147756A5008216039 @default.
- W1567147756 hasAuthorship W1567147756A5030620823 @default.
- W1567147756 hasAuthorship W1567147756A5051701996 @default.
- W1567147756 hasAuthorship W1567147756A5054936054 @default.
- W1567147756 hasAuthorship W1567147756A5064901353 @default.
- W1567147756 hasConcept C126322002 @default.
- W1567147756 hasConcept C134018914 @default.
- W1567147756 hasConcept C2776151105 @default.
- W1567147756 hasConcept C2777499176 @default.
- W1567147756 hasConcept C2779280383 @default.
- W1567147756 hasConcept C2779768347 @default.
- W1567147756 hasConcept C2781035296 @default.
- W1567147756 hasConcept C2911120302 @default.
- W1567147756 hasConcept C555293320 @default.
- W1567147756 hasConcept C556039675 @default.
- W1567147756 hasConcept C71924100 @default.
- W1567147756 hasConceptScore W1567147756C126322002 @default.
- W1567147756 hasConceptScore W1567147756C134018914 @default.
- W1567147756 hasConceptScore W1567147756C2776151105 @default.
- W1567147756 hasConceptScore W1567147756C2777499176 @default.
- W1567147756 hasConceptScore W1567147756C2779280383 @default.
- W1567147756 hasConceptScore W1567147756C2779768347 @default.
- W1567147756 hasConceptScore W1567147756C2781035296 @default.
- W1567147756 hasConceptScore W1567147756C2911120302 @default.
- W1567147756 hasConceptScore W1567147756C555293320 @default.
- W1567147756 hasConceptScore W1567147756C556039675 @default.
- W1567147756 hasConceptScore W1567147756C71924100 @default.
- W1567147756 hasIssue "3" @default.
- W1567147756 hasLocation W15671477561 @default.
- W1567147756 hasOpenAccess W1567147756 @default.
- W1567147756 hasPrimaryLocation W15671477561 @default.
- W1567147756 hasRelatedWork W1503511011 @default.