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• W1567164445 endingPage "10704" @default.
• W1567164445 startingPage "10686" @default.
• W1567164445 abstract "Nanoporous SnO2 thin films were elaborated to serve as sensing electrodes for label-free DNA detection using electrochemical impedance spectroscopy (EIS). Films were deposited by an electrodeposition process (EDP). Then the non-Faradic EIS behaviour was thoroughly investigated during some different steps of functionalization up to DNA hybridization. The results have shown a systematic decrease of the impedance upon DNA hybridization. The impedance decrease is attributed to an enhanced penetration of ionic species within the film volume. Besides, the comparison of impedance variations upon DNA hybridization between the liquid and vapour phase processes for organosilane (APTES) grafting on the nanoporous SnO2 films showed that vapour-phase method is more efficient. This is due to the fact that the vapour is more effective than the solution in penetrating the nanopores of the films. As a result, the DNA sensors built from vapour-treated silane layer exhibit a higher sensitivity than those produced from liquid-treated silane, in the range of tested target DNA concentration going to 10 nM. Finally, the impedance and fluorescence response signals strongly depend on the types of target DNA molecules, demonstrating a high selectivity of the process on nanoporous SnO2 films." @default.
• W1567164445 created "2016-06-24" @default.
• W1567164445 creator A5008104483 @default.
• W1567164445 creator A5029795075 @default.
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• W1567164445 date "2015-05-06" @default.
• W1567164445 modified "2023-10-06" @default.
• W1567164445 title "A Label-Free Impedimetric DNA Sensor Based on a Nanoporous SnO2 Film: Fabrication and Detection Performance" @default.
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• W1567164445 doi "https://doi.org/10.3390/s150510686" @default.
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• W1567164445 hasPublicationYear "2015" @default.
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