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- W1567180988 abstract "Abstract The appearance of viral induced antigen(s) on Sindbis and Semliki Forest (SF) virus-infected chick embryo cells is detected with homologous mouse anti-viral antibody-dependent, complement-mediated cytolysis in a 51Cr release assay. Such antigen(s) is detected within 3 to 4 hr after infection whereas viral cytopathologic effects do not occur until 10 to 12 hr. In addition, significant heterologous cytolysis (anti-Sindbis on SF virus-infected cells, or, anti-SFV on Sindbis-infected cells) could be observed with serum samples tested. These sera were assayed for neutralizing and hemagglutination-inhibition activities. Heterologous cytolysis cannot be correlated with hemagglutination-inhibition antibody titers nor is cross-neutralizing antibody detected. The possibility is discussed that another previously undefined antigen on infected cell membranes may be involved in heterologous cytolysis." @default.
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- W1567180988 date "1977-10-01" @default.
- W1567180988 modified "2023-09-27" @default.
- W1567180988 title "Antibody-Dependent, Complement-Mediated Homologous and Cross-Cytolysis of Togavirus-Infected Cells" @default.
- W1567180988 doi "https://doi.org/10.4049/jimmunol.119.4.1289" @default.
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