FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567200103> ?p ?o ?g. }

• W1567200103 endingPage "3579" @default.
• W1567200103 startingPage "3573" @default.
• W1567200103 abstract "A unique population of T lymphocytes, designated dendritic epidermal T cells (DETC), homes to the murine epidermis during fetal development. DETC express a canonical gammadelta TCR, Vgamma3/Vdelta1, which recognizes Ag expressed on damaged, stressed, or transformed keratinocytes. Recently, DETC were shown to play a key role in the complex process of wound repair. To examine the role of the DETC TCR in DETC localization to the epidermis, maintenance in the skin, and activation in vivo, we analyzed DETC in the TCRdelta(-/-) mouse. Unlike previous reports in which the TCRdelta(-/-) skin was found to be devoid of any DETC, we discovered that TCRdelta(-/-) mice have alphabeta TCR-expressing DETC with a polyclonal Vbeta chain repertoire. The alphabeta DETC are not retained over the life of the animal, suggesting that the gammadelta TCR is critical for the maintenance of DETC in the skin. Although the alphabeta DETC can be activated in response to direct stimulation, they do not respond to keratinocyte damage. Our results suggest that a keratinocyte-responsive TCR is necessary for DETC activation in response to keratinocyte damage and for DETC maintenance in the epidermis." @default.
• W1567200103 created "2016-06-24" @default.
• W1567200103 creator A5006563376 @default.
• W1567200103 creator A5036066088 @default.
• W1567200103 creator A5066590877 @default.
• W1567200103 creator A5070695623 @default.
• W1567200103 date "2004-03-15" @default.
• W1567200103 modified "2023-10-17" @default.
• W1567200103 title "A Keratinocyte-Responsive γδ TCR Is Necessary for Dendritic Epidermal T Cell Activation by Damaged Keratinocytes and Maintenance in the Epidermis" @default.
• W1567200103 cites W1493563927 @default.
• W1567200103 cites W1495055286 @default.
• W1567200103 cites W1511705708 @default.
• W1567200103 cites W1514347981 @default.
• W1567200103 cites W1653812454 @default.
• W1567200103 cites W1660648079 @default.
• W1567200103 cites W1920167267 @default.
• W1567200103 cites W1975163371 @default.
• W1567200103 cites W1981563612 @default.
• W1567200103 cites W1996642422 @default.
• W1567200103 cites W2003673339 @default.
• W1567200103 cites W2007243966 @default.
• W1567200103 cites W2014012740 @default.
• W1567200103 cites W2025799038 @default.
• W1567200103 cites W2027168093 @default.
• W1567200103 cites W2043462667 @default.
• W1567200103 cites W2053388673 @default.
• W1567200103 cites W2082226019 @default.
• W1567200103 cites W2091554825 @default.
• W1567200103 cites W2092084302 @default.
• W1567200103 cites W2104106789 @default.
• W1567200103 cites W2104915285 @default.
• W1567200103 cites W2113837213 @default.
• W1567200103 cites W2114951959 @default.
• W1567200103 cites W2114963681 @default.
• W1567200103 cites W2126043518 @default.
• W1567200103 cites W2129866279 @default.
• W1567200103 cites W2149480742 @default.
• W1567200103 cites W2182434027 @default.
• W1567200103 cites W4313379132 @default.
• W1567200103 cites W8161482 @default.
• W1567200103 doi "https://doi.org/10.4049/jimmunol.172.6.3573" @default.
• W1567200103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15004158" @default.
• W1567200103 hasPublicationYear "2004" @default.
• W1567200103 type Work @default.
• W1567200103 sameAs 1567200103 @default.
• W1567200103 citedByCount "126" @default.
• W1567200103 countsByYear W15672001032012 @default.
• W1567200103 countsByYear W15672001032013 @default.
• W1567200103 countsByYear W15672001032014 @default.
• W1567200103 countsByYear W15672001032015 @default.
• W1567200103 countsByYear W15672001032016 @default.
• W1567200103 countsByYear W15672001032017 @default.
• W1567200103 countsByYear W15672001032018 @default.
• W1567200103 countsByYear W15672001032019 @default.
• W1567200103 countsByYear W15672001032020 @default.
• W1567200103 countsByYear W15672001032021 @default.
• W1567200103 countsByYear W15672001032022 @default.
• W1567200103 countsByYear W15672001032023 @default.
• W1567200103 crossrefType "journal-article" @default.
• W1567200103 hasAuthorship W1567200103A5006563376 @default.
• W1567200103 hasAuthorship W1567200103A5036066088 @default.
• W1567200103 hasAuthorship W1567200103A5066590877 @default.
• W1567200103 hasAuthorship W1567200103A5070695623 @default.
• W1567200103 hasBestOaLocation W15672001031 @default.
• W1567200103 hasConcept C105702510 @default.
• W1567200103 hasConcept C19317047 @default.
• W1567200103 hasConcept C202751555 @default.
• W1567200103 hasConcept C203014093 @default.
• W1567200103 hasConcept C2776090121 @default.
• W1567200103 hasConcept C2776458125 @default.
• W1567200103 hasConcept C2777074287 @default.
• W1567200103 hasConcept C54355233 @default.
• W1567200103 hasConcept C86803240 @default.
• W1567200103 hasConcept C8891405 @default.
• W1567200103 hasConcept C95444343 @default.
• W1567200103 hasConceptScore W1567200103C105702510 @default.
• W1567200103 hasConceptScore W1567200103C19317047 @default.
• W1567200103 hasConceptScore W1567200103C202751555 @default.
• W1567200103 hasConceptScore W1567200103C203014093 @default.
• W1567200103 hasConceptScore W1567200103C2776090121 @default.
• W1567200103 hasConceptScore W1567200103C2776458125 @default.
• W1567200103 hasConceptScore W1567200103C2777074287 @default.
• W1567200103 hasConceptScore W1567200103C54355233 @default.
• W1567200103 hasConceptScore W1567200103C86803240 @default.
• W1567200103 hasConceptScore W1567200103C8891405 @default.
• W1567200103 hasConceptScore W1567200103C95444343 @default.
• W1567200103 hasIssue "6" @default.
• W1567200103 hasLocation W15672001031 @default.
• W1567200103 hasLocation W15672001032 @default.
• W1567200103 hasOpenAccess W1567200103 @default.
• W1567200103 hasPrimaryLocation W15672001031 @default.
• W1567200103 hasRelatedWork W1567200103 @default.
• W1567200103 hasRelatedWork W1583700542 @default.
• W1567200103 hasRelatedWork W2021274172 @default.
• W1567200103 hasRelatedWork W2022674745 @default.
• W1567200103 hasRelatedWork W2030037941 @default.
• W1567200103 hasRelatedWork W2107928168 @default.
• W1567200103 hasRelatedWork W2747317233 @default.

• next