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- W1567206378 abstract "1. The inhibitory effect of aurintricarboxylic acid on the RNA-binding abilities of rat liver 40-S ribosome subunits was investigated. 2. The RNA-binding ability of 40-S ribosome subunits, which had lost their RNA-binding ability due to treatment with 0.5 M salt (KCl and NH4 Cl) solution, is restored by addition of salt-washed protein fractions, prepared from rat liver ribosomes. 3. Aurintricarboxylic acid interacts and forms complexes with both salt-washed protein fractions, and 0.5 M salt-treated 40-S ribosome subunits. 4. The bound inhibitor prevents the association of salt washed protein fractions with 0.5 M salt-treated 40-S ribosome subunits. Consequently, the restoration of the RNA-binding ability of 40-S ribosome subunits is inhibited." @default.
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- W1567206378 date "1974-05-01" @default.
- W1567206378 modified "2023-09-24" @default.
- W1567206378 title "Interaction of informational macromolecules with ribosomes" @default.
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- W1567206378 doi "https://doi.org/10.1016/0005-2787(74)90079-3" @default.
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