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- W1567233573 abstract "An enzymic system of sheep vesicular gland which forms prostaglandins showed a time-dependent, concentration-dependent activation by phenol before full dioxygenase activity could be manifested. The activation process could be reversibly inhibited by o-phenanthroline. Aspirin and indomethacin did not instantly inhibit the dioxygenase, but acted in a time-dependent, concentration-dependent manner to block full activity of the synthetic system in an irreversible manner. The enzyme preparation was protected from the inhibitory action of these drugs by the presence of o-phenanthroline." @default.
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- W1567233573 date "1971-11-01" @default.
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- W1567233573 title "Stimulation and Blockade of Prostaglandin Biosynthesis" @default.
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- W1567233573 doi "https://doi.org/10.1016/s0021-9258(19)34171-7" @default.
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