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• W1567234787 abstract "Objetivo: Avaliar e comparar a concentracao de α-tocoferol no leite colostro e no soro de maes diabeticas e saudaveis. Metodos: Estudo transversal, realizado com 51 partu- rientes voluntarias, sendo 20 diagnosticadas com diabetes melito gestacional e 31 sem nenhuma doenca associada. Coletaram-se as amostras de soro e de colostro em jejum no pos-parto imediato e o α-tocoferol foi analisado por cromato- grafia liquida de alta eficiencia (CLAE). Para definir o estado nutricional de vitamina E, adotou-se ponto de corte serico (697,7µg/dL). O teste t de Student para variaveis indepen- dentes comparou as concentracoes medias de α-tocoferol no soro e no colostro entre os grupos controle e com diabetes melito gestacional. A correlacao de Pearson testou a relacao entre a concentracao de α-tocoferol no soro e no colostro para ambos os grupos. As diferencas foram consideradas significantes quando p<0,05. Resultados: As concentracoes de α-tocoferol no colostro foram 1.483,1±533,8µg/dL para as mulheres do Grupo Controle e 1.368,8±681,8µg/dL para as di- abeticas, nao havendo diferencas (p=0,50). Entretanto, no soro das puerperas controle, a concentracao de α-tocoferol foi 1.059,5±372,7µg/dL e, nas diabeticas, 1.391,4±531,5µg/dL, com p<0,01. Nao houve correlacao entre a concentracao de α-tocoferol no soro e no colostro para o Grupo Controle. Resultado semelhante foi encon- trado para o grupo com diabetes melito gestacional. Conclusoes: Os grupos apresentaram estado nutricional adequado quanto a vitamina E. Nao houve associacao entre diabetes melito gestacional e mudancas na concentracao de α-tocoferol no colostro. ABSTRACT Objective: To evaluate and compare the levels of α-tocopherol in colostrum and in the serum of healthy and diabetic mothers. Methods: This cross-sectional study enrolled 51 volun- teer mothers, 20 with the diagnosis of gestational diabetes mellitus and 31 without associated diseases. Serum and co- lostrum samples were collected in fasting in the immediate postpartum period and α-tocopherol was analyzed by high performance liquid chromatography (HPLC). In order to define the nutritional status of vitamin E, the cutoff point for the serum (697.7µg/dL) was adopted. Student's t-test for independent variables compared the average concentra- tions of α-tocopherol in the serum and in the colostrum between control and gestational diabetes mellitus groups. Pearson's correlation was used to assess the relationship between the concentration of α-tocopherol in serum and colostrum for both groups. Differences were considered significant when p<0.05." @default.
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• W1567234787 date "2014-06-01" @default.
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• W1567234787 title "Concentração de α-tocoferol no soro e colostro de mães com diabetes melito gestacional" @default.
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