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• W1567256096 abstract "Utilizing this unique animal model of thrombosis we demonstrated that human (IgG, IgM or IgA) polyclonal and monoclonal antiphospholipid antibodies derived from APS patients have a significant enhancing effect on thrombus formation. This effect is reversed by treatment of the mice with hydroxychloroquine (plaquenil). In addition murine polyclonal and monoclonal anticardiolipin antibodies induced by active immunization with human β 2 -GP1 or human anticardiolipin antibodies showed to have thrombogenic properties in CD1 mice. Antibodies with antihuman β 2 -GP1 activity alone did not seem to affect thrombus formation." @default.
• W1567256096 created "2016-06-24" @default.
• W1567256096 creator A5010995277 @default.
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• W1567256096 date "1996-10-01" @default.
• W1567256096 modified "2023-10-14" @default.
• W1567256096 title "<i>In Vivo</i> Models of Thrombosis for the Antiphospholipid Syndrome" @default.
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• W1567256096 doi "https://doi.org/10.1177/096120339600500524" @default.
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