Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567277466> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1567277466 endingPage "518" @default.
- W1567277466 startingPage "515" @default.
- W1567277466 abstract "Aim To evaluate the metabolic control and β-cell function 1 yr after the end of the European multicentre randomized Pediatric Onset Study. Methods Of 154 study patients, 131 were re-examined 24 months after type 1 diabetes onset (49.6% boys, age at onset 8.9 ± 4.3 yrs). Of which, 62 patients belonged to the primary group of the main study applying a sensor-augmented pump system during the first yr and 69 patients to the control group performing conventional insulin pump therapy with self-monitoring blood glucose. HbA1c, fasting blood glucose, and C-peptide were centrally measured (Clinical Trail Registration Number: ISRCTN05450731). Results At 24 months, i.e., 1 yr after the end of the interventional study, 52.4% of the patients used the sensor-augmented pump system, 46.0% conventional pump, and 1.6% multiple daily injections. HbA1c was 7.6 ± 1.3% in the primary and 7.7 ± 1.2% in the control group (p = 0.493). Frequent sensor use during the first yr was associated with statistically insignificant lowering of the HbA1c at 24 months (p = 0.236) as compared with irregular or no sensor use (7.4 ± 1.0% vs. 7.7 ± 1.3%). Although fasting C-peptide was not clearly different between the primary and control group (0.13 ± 0.17 vs. 0.09 ± 0.10 nmol/L, p = 0.121), patients with frequent sensor use had significantly less C-peptide loss within 24 months (C-peptide reduction 0.02 ± 0.18 vs. 0.07 ± 0.11 nmol/L, p = 0.046). There was no difference between the groups regarding daily insulin requirements. Conclusion Sensor-augmented pump therapy from onset of diabetes may lead to better long-term glycemic control and help to preserve endogenous β-cell function, if patients comply with frequent use of continuous glucose monitoring. © 2012 John Wiley & Sons A/S" @default.
- W1567277466 created "2016-06-24" @default.
- W1567277466 creator A5002273933 @default.
- W1567277466 creator A5017305166 @default.
- W1567277466 creator A5021568045 @default.
- W1567277466 creator A5022646816 @default.
- W1567277466 creator A5024413040 @default.
- W1567277466 creator A5038117804 @default.
- W1567277466 creator A5063531383 @default.
- W1567277466 creator A5086131799 @default.
- W1567277466 date "2012-04-05" @default.
- W1567277466 modified "2023-10-10" @default.
- W1567277466 title "Sensor augmented pump therapy from onset of type 1 diabetes: late follow-up results of the Pediatric Onset Study" @default.
- W1567277466 cites W1966350212 @default.
- W1567277466 cites W1988519907 @default.
- W1567277466 cites W2166158593 @default.
- W1567277466 cites W2734011609 @default.
- W1567277466 doi "https://doi.org/10.1111/j.1399-5448.2012.00863.x" @default.
- W1567277466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22487079" @default.
- W1567277466 hasPublicationYear "2012" @default.
- W1567277466 type Work @default.
- W1567277466 sameAs 1567277466 @default.
- W1567277466 citedByCount "30" @default.
- W1567277466 countsByYear W15672774662012 @default.
- W1567277466 countsByYear W15672774662013 @default.
- W1567277466 countsByYear W15672774662014 @default.
- W1567277466 countsByYear W15672774662015 @default.
- W1567277466 countsByYear W15672774662016 @default.
- W1567277466 countsByYear W15672774662018 @default.
- W1567277466 countsByYear W15672774662019 @default.
- W1567277466 countsByYear W15672774662020 @default.
- W1567277466 countsByYear W15672774662021 @default.
- W1567277466 countsByYear W15672774662022 @default.
- W1567277466 countsByYear W15672774662023 @default.
- W1567277466 crossrefType "journal-article" @default.
- W1567277466 hasAuthorship W1567277466A5002273933 @default.
- W1567277466 hasAuthorship W1567277466A5017305166 @default.
- W1567277466 hasAuthorship W1567277466A5021568045 @default.
- W1567277466 hasAuthorship W1567277466A5022646816 @default.
- W1567277466 hasAuthorship W1567277466A5024413040 @default.
- W1567277466 hasAuthorship W1567277466A5038117804 @default.
- W1567277466 hasAuthorship W1567277466A5063531383 @default.
- W1567277466 hasAuthorship W1567277466A5086131799 @default.
- W1567277466 hasBestOaLocation W15672774661 @default.
- W1567277466 hasConcept C126322002 @default.
- W1567277466 hasConcept C134018914 @default.
- W1567277466 hasConcept C187212893 @default.
- W1567277466 hasConcept C2777180221 @default.
- W1567277466 hasConcept C2778875212 @default.
- W1567277466 hasConcept C2779306644 @default.
- W1567277466 hasConcept C2779794567 @default.
- W1567277466 hasConcept C2781232474 @default.
- W1567277466 hasConcept C555293320 @default.
- W1567277466 hasConcept C70818257 @default.
- W1567277466 hasConcept C71924100 @default.
- W1567277466 hasConceptScore W1567277466C126322002 @default.
- W1567277466 hasConceptScore W1567277466C134018914 @default.
- W1567277466 hasConceptScore W1567277466C187212893 @default.
- W1567277466 hasConceptScore W1567277466C2777180221 @default.
- W1567277466 hasConceptScore W1567277466C2778875212 @default.
- W1567277466 hasConceptScore W1567277466C2779306644 @default.
- W1567277466 hasConceptScore W1567277466C2779794567 @default.
- W1567277466 hasConceptScore W1567277466C2781232474 @default.
- W1567277466 hasConceptScore W1567277466C555293320 @default.
- W1567277466 hasConceptScore W1567277466C70818257 @default.
- W1567277466 hasConceptScore W1567277466C71924100 @default.
- W1567277466 hasIssue "7" @default.
- W1567277466 hasLocation W15672774661 @default.
- W1567277466 hasLocation W15672774662 @default.
- W1567277466 hasOpenAccess W1567277466 @default.
- W1567277466 hasPrimaryLocation W15672774661 @default.
- W1567277466 hasRelatedWork W2013772536 @default.
- W1567277466 hasRelatedWork W2059198830 @default.
- W1567277466 hasRelatedWork W2074138148 @default.
- W1567277466 hasRelatedWork W2076148029 @default.
- W1567277466 hasRelatedWork W2076556143 @default.
- W1567277466 hasRelatedWork W2133082929 @default.
- W1567277466 hasRelatedWork W2404062608 @default.
- W1567277466 hasRelatedWork W4367057200 @default.
- W1567277466 hasRelatedWork W95215043 @default.
- W1567277466 hasRelatedWork W1523527470 @default.
- W1567277466 hasVolume "13" @default.
- W1567277466 isParatext "false" @default.
- W1567277466 isRetracted "false" @default.
- W1567277466 magId "1567277466" @default.
- W1567277466 workType "article" @default.