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- W1567364560 endingPage "1978" @default.
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- W1567364560 abstract "Fibrosis of the lung, a common complication of systemic sclerosis (SSc) and the hallmark of idiopathic pulmonary fibrosis (IPF), is associated with substantial mortality and has no approved therapy. Despite some degree of overlap in their clinical features and pathogenesis, SSc-associated interstitial lung disease (ILD) and IPF have differences, with significant implications for diagnosis, evaluation, and management. To shed light on these issues, this review compares and contrasts salient features of these 2 entities, focusing on clinical manifestations, lung imaging, and pathology, along with current concepts of pathogenesis, including animal models, translational studies, genetic factors, and predictive biomarkers. We conclude by posing questions that might unveil new areas of investigation and inform novel and targeted approaches to therapy." @default.
- W1567364560 created "2016-06-24" @default.
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- W1567364560 date "2014-07-28" @default.
- W1567364560 modified "2023-10-10" @default.
- W1567364560 title "Review: Interstitial Lung Disease Associated With Systemic Sclerosis and Idiopathic Pulmonary Fibrosis: How Similar and Distinct?" @default.
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- W1567364560 doi "https://doi.org/10.1002/art.38702" @default.
- W1567364560 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4340472" @default.
- W1567364560 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24838199" @default.
- W1567364560 hasPublicationYear "2014" @default.
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