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- W1567388072 abstract "Objective: To test the function of endothelial cells transfected eNOS gene.Methods: To test the function of eNOS-overexpressing endothelial cells inhibiting smooth muscle cell proliferation and platelet aggregation in vitro by colorimetry, MTT and 3H-TdR permeate, respectively.Results: The platelet aggregation is significiently decreasing between the groups of EC and eNOS at the different time (P<0.05), is 42.20 and 32.60 seperately at the time of 120h. The SMC proliferation is significiently decreasing between the groups of EC and eNOS at the different time (P<0.05). It is 0.28 and 0.22 by MTT test, 4691.83 and 3995.00 by 3H-TdR permeate, separately, at the time of 120h.Conclution: eNOS-overexpressing endothelial cells inhibited significantly smooth muscle cells proliferation and platelet aggregation in vitro; which showed powerful effection 48 hours post transfection and lasted up to 120 hours at the least; and were holden back by L-NAME." @default.
- W1567388072 created "2016-06-24" @default.
- W1567388072 date "2004-05-01" @default.
- W1567388072 modified "2023-09-24" @default.
- W1567388072 title "eNOS gene transfected endothelial cells inhibit smooth muscle cell proliferation and platelet aggregation in vitro" @default.
- W1567388072 doi "https://doi.org/10.1016/j.ymthe.2004.06.330" @default.
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