FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567391238> ?p ?o ?g. }

• W1567391238 endingPage "11382" @default.
• W1567391238 startingPage "11373" @default.
• W1567391238 abstract "Xenopus laevis oocytes contain a 38,000-Da protein which serves both as a 5 S gene-specific transcription initiation factor (TFIIIA) and to stabilize 5 S RNA in ribonucleoprotein complexes. Using an antibody to this protein we have measured the levels of TFIIIA during oogenesis and embryonic development in X. laevis. The maximal steady state level (approximately 10(12) molecules/oocyte) is reached early in oogenesis but drops 10- to 20-fold in later stages and another 10- to 20-fold during ovulation. The reduced amount present in the unfertilized egg remains at a nearly constant level throughout early development, but with cell division the cellular concentration drops from 3 X 10(9) to about 10(4) molecules/cell. An immunoreactive protein of the same size is also found in liver tissues and in cultured kidney cells, which also contain about 10(4) molecules/cell. By both structural (CNBr peptide analysis) and functional (transcription of 5 S genes) analyses the embryonic and kidney cell 38,000-Da factors appear indistinguishable from oocyte TFIIIA. In addition a second antigenically related protein of about 40,000 Da is found in late stage embryos, liver tissues, and adult kidney cells (where it is severalfold more abundant than the 38,000-Da TFIIIA). The chromatographic fractionation and functional analysis of the kidney cell extracts has shown that fractions containing the 38,000-Da protein support 5 S RNA synthesis while fractions containing the 40,000-Da protein do not. The significance of these findings for 5 S gene regulation is discussed with respect to the dual function of TFIIIA, the presence of rate-limiting amounts of TFIIIA, and the possibility of stage-specific factors." @default.
• W1567391238 created "2016-06-24" @default.
• W1567391238 creator A5007755251 @default.
• W1567391238 creator A5039096233 @default.
• W1567391238 creator A5089754286 @default.
• W1567391238 date "1984-09-01" @default.
• W1567391238 modified "2023-09-30" @default.
• W1567391238 title "Altered levels of a 5 S gene-specific transcription factor (TFIIIA) during oogenesis and embryonic development of Xenopus laevis." @default.
• W1567391238 cites W140940636 @default.
• W1567391238 cites W1522226780 @default.
• W1567391238 cites W1550569215 @default.
• W1567391238 cites W1555656315 @default.
• W1567391238 cites W1558516755 @default.
• W1567391238 cites W1559177712 @default.
• W1567391238 cites W1561042132 @default.
• W1567391238 cites W1864119499 @default.
• W1567391238 cites W1968120710 @default.
• W1567391238 cites W1969001854 @default.
• W1567391238 cites W1969842104 @default.
• W1567391238 cites W1975594346 @default.
• W1567391238 cites W1978660686 @default.
• W1567391238 cites W1980424753 @default.
• W1567391238 cites W1981073602 @default.
• W1567391238 cites W1981815989 @default.
• W1567391238 cites W1982233852 @default.
• W1567391238 cites W1987207913 @default.
• W1567391238 cites W1991214910 @default.
• W1567391238 cites W1992815962 @default.
• W1567391238 cites W1999241341 @default.
• W1567391238 cites W2005107879 @default.
• W1567391238 cites W2006624258 @default.
• W1567391238 cites W2007490638 @default.
• W1567391238 cites W2012972361 @default.
• W1567391238 cites W2014091873 @default.
• W1567391238 cites W2024651141 @default.
• W1567391238 cites W2032344196 @default.
• W1567391238 cites W2032410345 @default.
• W1567391238 cites W2035627599 @default.
• W1567391238 cites W2038597359 @default.
• W1567391238 cites W2040487729 @default.
• W1567391238 cites W2064865590 @default.
• W1567391238 cites W2066157280 @default.
• W1567391238 cites W2073255014 @default.
• W1567391238 cites W2075978320 @default.
• W1567391238 cites W2082532569 @default.
• W1567391238 cites W2086195230 @default.
• W1567391238 cites W2093527278 @default.
• W1567391238 cites W2100837269 @default.
• W1567391238 cites W2104404316 @default.
• W1567391238 cites W2107332774 @default.
• W1567391238 cites W2109448523 @default.
• W1567391238 cites W2147355227 @default.
• W1567391238 cites W2150438280 @default.
• W1567391238 cites W2152528574 @default.
• W1567391238 cites W2190230654 @default.
• W1567391238 cites W2316528406 @default.
• W1567391238 doi "https://doi.org/10.1016/s0021-9258(18)90871-9" @default.
• W1567391238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6206067" @default.
• W1567391238 hasPublicationYear "1984" @default.
• W1567391238 type Work @default.
• W1567391238 sameAs 1567391238 @default.
• W1567391238 citedByCount "96" @default.
• W1567391238 countsByYear W15673912382012 @default.
• W1567391238 countsByYear W15673912382013 @default.
• W1567391238 countsByYear W15673912382014 @default.
• W1567391238 countsByYear W15673912382015 @default.
• W1567391238 countsByYear W15673912382019 @default.
• W1567391238 crossrefType "journal-article" @default.
• W1567391238 hasAuthorship W1567391238A5007755251 @default.
• W1567391238 hasAuthorship W1567391238A5039096233 @default.
• W1567391238 hasAuthorship W1567391238A5089754286 @default.
• W1567391238 hasBestOaLocation W15673912381 @default.
• W1567391238 hasConcept C104317684 @default.
• W1567391238 hasConcept C145103041 @default.
• W1567391238 hasConcept C163949779 @default.
• W1567391238 hasConcept C196843134 @default.
• W1567391238 hasConcept C2779535977 @default.
• W1567391238 hasConcept C54355233 @default.
• W1567391238 hasConcept C86339819 @default.
• W1567391238 hasConcept C86803240 @default.
• W1567391238 hasConcept C87073359 @default.
• W1567391238 hasConcept C95444343 @default.
• W1567391238 hasConceptScore W1567391238C104317684 @default.
• W1567391238 hasConceptScore W1567391238C145103041 @default.
• W1567391238 hasConceptScore W1567391238C163949779 @default.
• W1567391238 hasConceptScore W1567391238C196843134 @default.
• W1567391238 hasConceptScore W1567391238C2779535977 @default.
• W1567391238 hasConceptScore W1567391238C54355233 @default.
• W1567391238 hasConceptScore W1567391238C86339819 @default.
• W1567391238 hasConceptScore W1567391238C86803240 @default.
• W1567391238 hasConceptScore W1567391238C87073359 @default.
• W1567391238 hasConceptScore W1567391238C95444343 @default.
• W1567391238 hasIssue "18" @default.
• W1567391238 hasLocation W15673912381 @default.
• W1567391238 hasOpenAccess W1567391238 @default.
• W1567391238 hasPrimaryLocation W15673912381 @default.
• W1567391238 hasRelatedWork W193505503 @default.
• W1567391238 hasRelatedWork W1977415789 @default.

• next