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• W1567394542 abstract "Article1 July 1957HEART DISEASE OF UNKNOWN CAUSE IN SIBLINGSJAMES H. AVERILL, RAYMOND V. RANDALL, ELLIS JOFFE, PAUL D. WHITE, M.A.C.P.JAMES H. AVERILLSearch for more papers by this author, RAYMOND V. RANDALLSearch for more papers by this author, ELLIS JOFFESearch for more papers by this author, PAUL D. WHITE, M.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-1-49 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHeart disease of unknown etiology is rare. It is even more unusual to find two or more members of one family with an obscure type of heart disease. It is the purpose of this paper to report 10 cases occurring in five pairs of siblings. All died from their disease, and a postmortem examination was performed in seven cases, namely, in both siblings from two pairs and in one sibling from each of the other three pairs. Although the pathologic findings varied, there was a similarity in the clinical course of these patients. Pathologically, endocardial fibro-elastosis, myocardial hypertrophy and myocardial...Bibliography1. White PD: Heart disease, 4th Ed., 1951, The Macmillan Company, New York, p. 280. Google Scholar2. AddariiMartiniMahainWinston FLIMR: Nouvelles recherches sur le bloc bilateral manque, Cardiologia 11: 36-59, 1949. CrossrefGoogle Scholar3. Evans W: Familial cardiomegaly, Brit. Heart J. 11: 68-82, 1949. CrossrefMedlineGoogle Scholar4. Simkins S: Idiopathic cardiac hypertrophy in adults, Am. Heart J. 42: 453-459, 1951. CrossrefMedlineGoogle Scholar5. DaviesMarvelGenovese RRRJPD: Heart disease of unknown etiology, Am. Heart J. 42: 546-565, 1951. CrossrefMedlineGoogle Scholar6. WeinbergHimelfarb TAJ: Endocardial fibroelastosis (so-called fetal endocarditis). A report of two cases occurring in siblings, Bull. Johns Hopkins Hosp. 72: 299-306, 1943. Google Scholar7. BlumbergLyon RWRA: Endocardial sclerosis, Am. J. Dis. Child. 84: 291-308, 1952. Google Scholar8. Ullrich O: Angeborene Herzhypertrophie mit Endokard fibrose bei Zwei enineiigen Partnern von mannlichen Drillingen, Ztschr. f. mensche Vererb. u. Konstitutionslehre 21: 585-598, 1938. Google Scholar9. Case Records of the Massachusetts General Hospital No. 28042, New England J. Med. 246: 158-161, 1942. Google Scholar9. Sommers B (a) : Problems in the clinical diagnosis and classification of ventricular hypertrophy in adults. III. Familial cardiopathy, Minnesota Med. 39: 153-156 (Mar.) 1956. MedlineGoogle Scholar10. Gould SE: Pathology of the heart, 1953, Charles C. Thomas, Publisher, Springfield, Illinois. Google Scholar11. Gross P: Concept of fetal endocarditis: a general review with report of an illustrative case, Arch. Path. 31: 163-177, 1941. Google Scholar12. Craig JM: Congenital endocardial sclerosis, Internat. A. M. Museums Bull. 30: 15-67, 1949. Google Scholar13. Davies JN: Endocardial fibrosis in Africans, East African M. J. 25: 10-14, 1948. Google Scholar14. ThomasRandallBlandCastleman WARVEFB: Endocardial fibro-elastosis: factor in heart disease of obscure etiology, New England J. Med. 251: 327-338, 1954. CrossrefMedlineGoogle Scholar15. BurwellRobin CSED: Pericardial constriction versus myocardial fibrosis, presented before the New England Cardiovascular Society on January 4, 1954. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication August 29, 1956.Requests for reprints should be addressed to James H. Averill, M.D., 264 Elm Street, Northampton, Massachusetts. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAccountability and the ECBEndocardial fibroelastosis: Family studies withspecial reference to counselingFamilial occurrence of the contracted form of endocardial fibroelastosisFamiliäre Kardiomegalie auf der Basis einer EndomyokardfibroseFamilial primary amyloidosis with severe amyloid heart diseaseHereditary cardiovascular dysplasiaFamilial cardiomyopathyCardiomegaly of Unknown Cause Occurring in a FamilyAdult Endocardial Fibroelastosis Associated with Dextrocardia and Situs Inversus 1 July 1957Volume 47, Issue 1Page: 49-58KeywordsArrhythmiaAutopsyCardiac hypertrophyCardiovascular therapyEtiologyFibrosis ePublished: 1 December 2008 Issue Published: 1 July 1957 PDF downloadLoading ..." @default.
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