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- W1567397268 abstract "Publisher Summary Neurophysiological studies constitute an important step in the evaluation of the resultant disorders. This chapter discusses the role of clinical neurophysiology in the evaluation of toxic neuropathies. Three significant applications that are discussed in the chapter are as follows: (1) clinical neurophysiology, in conjunction with clinical and pathological evaluations, provides useful information in classifying toxic peripheral neuropathies and delineating the anatomical-pathological nature of neuropathy, (2) neurophysiological studies are useful in the surveillance of clinical and subclinical deficits, resulting from environmental and industrial contact, with metallic and chemical peripheral nerve toxins, and (3) neurophysiological studies have been used to monitor the toxic effect of several valuable drugs, primarily antineoplastic agents, on the peripheral nerve, and to infer dose neurotoxicity relationships. Neurophysiological studies are also used to monitor the toxic effect of environmental and occupational toxins on the peripheral nerves. Most of the work in this area is performed on lead neurotoxicity and reasonable dose neurotoxicity relationships are found. However, as there are several other peripheral nerve toxins that act differently, a concerted collaborative effort, involving occupational medicine specialists, environmentalists, biochemists, and clinical neurophysiologists, is required in several geographical locations to determine such cause/dose effects for other toxins." @default.
- W1567397268 created "2016-06-24" @default.
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- W1567397268 date "2002-01-01" @default.
- W1567397268 modified "2023-09-27" @default.
- W1567397268 title "Chapter 13 An appraisal of the role of clinical neurophysiology in toxic neuropathy" @default.
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