Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567413298> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1567413298 endingPage "74" @default.
- W1567413298 startingPage "169" @default.
- W1567413298 abstract "The effects of juice from Morinda citrifolia (noni) on gastric emptying, gastrointestinal transit, and plasma level of cholecystokinin (CCK) in rats were studied. Male rats were given noni by gavage at levels of 0.25, 1, or 4 ml/kg once per day for one or 7 days. The rats in the control group were given water, while the rats in the experimental group were fasted overnight before measurement of gastrointestinal motility. Gastrointestinal motility was assessed in rats 15 min after intragastric instillation of a test meal containing charcoal (10%) and Na251CrO4 (0.5 microCi/ml). Gastric emptying was determined by measuring the amount of radiolabeled chromium contained in the small intestine as a percentage of the initial amount received. Then, gastrointestinal transit was evaluated by calculating the geometric center of distribution of the radiolabeled marker. Finally, blood samples were collected for measurement of CCK by radioimmunoassay. The administration of noni at 0.25 ml/kg, but not at 1 ml/kg and 4 ml/kg, for 1 day significantly inhibited gastric emptying. In contrast, gastric emptying was significantly inhibited by oral noni (0.25, 1, or 4 ml/kg) for 7 days. Intraperitoneal injection of lorglumide (5 or 10 mg/kg), a selective CCK1 receptor antagonist, effectively attenuated the noni-induced inhibition of gastric emptying. The intestinal transit and body weight, food intake, water intake, urine volume as well as feces weight were not altered by the administration of noni either acutely or chronically, but the administration of oral noni (1 ml/kg) for 7 days increased the level of plasma CCK in male rats. These results suggest that oral noni inhibits gastric emptying in male rats via a mechanism involving stimulation of CCK secretion and CCK1 receptor activation." @default.
- W1567413298 created "2016-06-24" @default.
- W1567413298 creator A5016889897 @default.
- W1567413298 creator A5032170703 @default.
- W1567413298 creator A5039890191 @default.
- W1567413298 creator A5045110474 @default.
- W1567413298 creator A5050104295 @default.
- W1567413298 creator A5076564117 @default.
- W1567413298 creator A5084785838 @default.
- W1567413298 date "2004-12-31" @default.
- W1567413298 modified "2023-09-25" @default.
- W1567413298 title "Effects of juice from Morinda citrifolia (Noni) on gastric emptying in male rats." @default.
- W1567413298 cites W1838613517 @default.
- W1567413298 cites W1951242895 @default.
- W1567413298 cites W1970772144 @default.
- W1567413298 cites W1986852617 @default.
- W1567413298 cites W1988646125 @default.
- W1567413298 cites W1991714764 @default.
- W1567413298 cites W1992897439 @default.
- W1567413298 cites W1994091958 @default.
- W1567413298 cites W2002400504 @default.
- W1567413298 cites W2024476894 @default.
- W1567413298 cites W2027824029 @default.
- W1567413298 cites W2039473138 @default.
- W1567413298 cites W2041619734 @default.
- W1567413298 cites W2048457541 @default.
- W1567413298 cites W2054009022 @default.
- W1567413298 cites W2055633767 @default.
- W1567413298 cites W2057272568 @default.
- W1567413298 cites W2062769140 @default.
- W1567413298 cites W2066944012 @default.
- W1567413298 cites W2068783457 @default.
- W1567413298 cites W2080975702 @default.
- W1567413298 cites W2112164509 @default.
- W1567413298 cites W2112852687 @default.
- W1567413298 cites W2123046580 @default.
- W1567413298 cites W2133069789 @default.
- W1567413298 cites W2139357378 @default.
- W1567413298 cites W2150448287 @default.
- W1567413298 cites W2167562456 @default.
- W1567413298 cites W2177315971 @default.
- W1567413298 cites W2182941164 @default.
- W1567413298 cites W2400881580 @default.
- W1567413298 cites W2461429252 @default.
- W1567413298 cites W2148827730 @default.
- W1567413298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15803749" @default.
- W1567413298 hasPublicationYear "2004" @default.
- W1567413298 type Work @default.
- W1567413298 sameAs 1567413298 @default.
- W1567413298 citedByCount "11" @default.
- W1567413298 countsByYear W15674132982012 @default.
- W1567413298 countsByYear W15674132982015 @default.
- W1567413298 countsByYear W15674132982019 @default.
- W1567413298 crossrefType "journal-article" @default.
- W1567413298 hasAuthorship W1567413298A5016889897 @default.
- W1567413298 hasAuthorship W1567413298A5032170703 @default.
- W1567413298 hasAuthorship W1567413298A5039890191 @default.
- W1567413298 hasAuthorship W1567413298A5045110474 @default.
- W1567413298 hasAuthorship W1567413298A5050104295 @default.
- W1567413298 hasAuthorship W1567413298A5076564117 @default.
- W1567413298 hasAuthorship W1567413298A5084785838 @default.
- W1567413298 hasConcept C126322002 @default.
- W1567413298 hasConcept C185592680 @default.
- W1567413298 hasConcept C2777056448 @default.
- W1567413298 hasConcept C2778345441 @default.
- W1567413298 hasConcept C2779308761 @default.
- W1567413298 hasConcept C2779422922 @default.
- W1567413298 hasConcept C3020479747 @default.
- W1567413298 hasConcept C556039675 @default.
- W1567413298 hasConcept C71924100 @default.
- W1567413298 hasConceptScore W1567413298C126322002 @default.
- W1567413298 hasConceptScore W1567413298C185592680 @default.
- W1567413298 hasConceptScore W1567413298C2777056448 @default.
- W1567413298 hasConceptScore W1567413298C2778345441 @default.
- W1567413298 hasConceptScore W1567413298C2779308761 @default.
- W1567413298 hasConceptScore W1567413298C2779422922 @default.
- W1567413298 hasConceptScore W1567413298C3020479747 @default.
- W1567413298 hasConceptScore W1567413298C556039675 @default.
- W1567413298 hasConceptScore W1567413298C71924100 @default.
- W1567413298 hasIssue "4" @default.
- W1567413298 hasLocation W15674132981 @default.
- W1567413298 hasOpenAccess W1567413298 @default.
- W1567413298 hasPrimaryLocation W15674132981 @default.
- W1567413298 hasRelatedWork W1567413298 @default.
- W1567413298 hasRelatedWork W1612817479 @default.
- W1567413298 hasRelatedWork W1920825700 @default.
- W1567413298 hasRelatedWork W1977140127 @default.
- W1567413298 hasRelatedWork W1994722112 @default.
- W1567413298 hasRelatedWork W2040136104 @default.
- W1567413298 hasRelatedWork W2044174926 @default.
- W1567413298 hasRelatedWork W2121086375 @default.
- W1567413298 hasRelatedWork W2141772255 @default.
- W1567413298 hasRelatedWork W2899084033 @default.
- W1567413298 hasVolume "47" @default.
- W1567413298 isParatext "false" @default.
- W1567413298 isRetracted "false" @default.
- W1567413298 magId "1567413298" @default.
- W1567413298 workType "article" @default.