FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567447617> ?p ?o ?g. }

• W1567447617 endingPage "829" @default.
• W1567447617 startingPage "822" @default.
• W1567447617 abstract "Background: MRI studies have shown gray-matter abnormalities in fatigued multiple sclerosis (MS) patients. However, given that physical disability is highly correlated to MS fatigue, it is often difficult to disentangle its effect in these MRI findings. Objective: The objective of this research paper is to investigate gray-matter damage in mildly disabled MS patients, addressing which variables were better related to fatigue while controlling for physical disability and depression. Methods: Forty-nine relapsing–remitting MS (RRMS) patients and 30 controls underwent MRI (3T). Fatigue was assessed using the Fatigue Severity Scale (FSS). Multivariate logistic regression was performed to assess the contribution of clinical and MRI metrics to fatigue. Statistical analyses were performed controlling for disability and depression. Results: Fatigue was present in 22 (44.9%) patients. FSS score was highly correlated with EDSS ( p = 0.00001). Patients with fatigue had lower brain cortical and subcortical gray-matter volumes. However, after controlling for EDSS, only the caudate and the accumbens volumes remained statistically significant. Conclusions: Fatigued MS patients have a global cortical and subcortical gray-matter atrophy that seems largely related to higher physical disability. However, striatal structures involved in effort-reward functions exhibited smaller volumes in fatigued patients, independently of physical disability and depressive symptoms, supporting the theory of cortico-striatal network impairment in MS fatigue." @default.
• W1567447617 created "2016-06-24" @default.
• W1567447617 creator A5014642734 @default.
• W1567447617 creator A5044809264 @default.
• W1567447617 creator A5069911965 @default.
• W1567447617 date "2015-08-03" @default.
• W1567447617 modified "2023-10-02" @default.
• W1567447617 title "Atrophy of reward-related striatal structures in fatigued MS patients is independent of physical disability" @default.
• W1567447617 cites W1572714703 @default.
• W1567447617 cites W1970009175 @default.
• W1567447617 cites W1990110979 @default.
• W1567447617 cites W2005139957 @default.
• W1567447617 cites W2014107126 @default.
• W1567447617 cites W2017544610 @default.
• W1567447617 cites W2055018246 @default.
• W1567447617 cites W2060275991 @default.
• W1567447617 cites W2060885643 @default.
• W1567447617 cites W2063665995 @default.
• W1567447617 cites W2064885604 @default.
• W1567447617 cites W2078873559 @default.
• W1567447617 cites W2097942023 @default.
• W1567447617 cites W2098642073 @default.
• W1567447617 cites W2106192626 @default.
• W1567447617 cites W2110208125 @default.
• W1567447617 cites W2112165124 @default.
• W1567447617 cites W2113319997 @default.
• W1567447617 cites W2114242035 @default.
• W1567447617 cites W2121302562 @default.
• W1567447617 cites W2122545833 @default.
• W1567447617 cites W2125184576 @default.
• W1567447617 cites W2135381668 @default.
• W1567447617 cites W2140362680 @default.
• W1567447617 cites W2151721316 @default.
• W1567447617 cites W2157707759 @default.
• W1567447617 cites W2170332928 @default.
• W1567447617 cites W2170689912 @default.
• W1567447617 cites W2315429401 @default.
• W1567447617 cites W2473786944 @default.
• W1567447617 doi "https://doi.org/10.1177/1352458515599451" @default.
• W1567447617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26238465" @default.
• W1567447617 hasPublicationYear "2015" @default.
• W1567447617 type Work @default.
• W1567447617 sameAs 1567447617 @default.
• W1567447617 citedByCount "33" @default.
• W1567447617 countsByYear W15674476172016 @default.
• W1567447617 countsByYear W15674476172017 @default.
• W1567447617 countsByYear W15674476172018 @default.
• W1567447617 countsByYear W15674476172019 @default.
• W1567447617 countsByYear W15674476172020 @default.
• W1567447617 countsByYear W15674476172021 @default.
• W1567447617 countsByYear W15674476172022 @default.
• W1567447617 countsByYear W15674476172023 @default.
• W1567447617 crossrefType "journal-article" @default.
• W1567447617 hasAuthorship W1567447617A5014642734 @default.
• W1567447617 hasAuthorship W1567447617A5044809264 @default.
• W1567447617 hasAuthorship W1567447617A5069911965 @default.
• W1567447617 hasConcept C118552586 @default.
• W1567447617 hasConcept C126322002 @default.
• W1567447617 hasConcept C139719470 @default.
• W1567447617 hasConcept C151956035 @default.
• W1567447617 hasConcept C15744967 @default.
• W1567447617 hasConcept C162324750 @default.
• W1567447617 hasConcept C1862650 @default.
• W1567447617 hasConcept C2776867660 @default.
• W1567447617 hasConcept C2779625216 @default.
• W1567447617 hasConcept C2780640218 @default.
• W1567447617 hasConcept C2780892749 @default.
• W1567447617 hasConcept C2781172350 @default.
• W1567447617 hasConcept C71924100 @default.
• W1567447617 hasConcept C99508421 @default.
• W1567447617 hasConceptScore W1567447617C118552586 @default.
• W1567447617 hasConceptScore W1567447617C126322002 @default.
• W1567447617 hasConceptScore W1567447617C139719470 @default.
• W1567447617 hasConceptScore W1567447617C151956035 @default.
• W1567447617 hasConceptScore W1567447617C15744967 @default.
• W1567447617 hasConceptScore W1567447617C162324750 @default.
• W1567447617 hasConceptScore W1567447617C1862650 @default.
• W1567447617 hasConceptScore W1567447617C2776867660 @default.
• W1567447617 hasConceptScore W1567447617C2779625216 @default.
• W1567447617 hasConceptScore W1567447617C2780640218 @default.
• W1567447617 hasConceptScore W1567447617C2780892749 @default.
• W1567447617 hasConceptScore W1567447617C2781172350 @default.
• W1567447617 hasConceptScore W1567447617C71924100 @default.
• W1567447617 hasConceptScore W1567447617C99508421 @default.
• W1567447617 hasIssue "6" @default.
• W1567447617 hasLocation W15674476171 @default.
• W1567447617 hasLocation W15674476172 @default.
• W1567447617 hasOpenAccess W1567447617 @default.
• W1567447617 hasPrimaryLocation W15674476171 @default.
• W1567447617 hasRelatedWork W153321022 @default.
• W1567447617 hasRelatedWork W2021395749 @default.
• W1567447617 hasRelatedWork W2101000495 @default.
• W1567447617 hasRelatedWork W2109158135 @default.
• W1567447617 hasRelatedWork W2121052475 @default.
• W1567447617 hasRelatedWork W2122454460 @default.
• W1567447617 hasRelatedWork W2126097335 @default.
• W1567447617 hasRelatedWork W2151162595 @default.
• W1567447617 hasRelatedWork W2167752445 @default.

• next