FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567449627> ?p ?o ?g. }

• W1567449627 endingPage "311" @default.
• W1567449627 startingPage "302" @default.
• W1567449627 abstract "To cite this article: Calderón MA, Simons FER, Malling H‐J, Lockey RF, Moingeon P, Demoly P. Sublingual allergen immunotherapy: mode of action and its relationship with the safety profile. Allergy 2012; 67 : 302–311. Abstract Allergen immunotherapy reorients inappropriate immune responses in allergic patients. Sublingual allergen immunotherapy (SLIT) has been approved, notably in the European Union, as an effective alternative to subcutaneous allergen immunotherapy (SCIT) for allergic rhinitis patients. Compared with SCIT, SLIT has a better safety profile. This is possibly because oral antigen‐presenting cells (mostly Langerhans and myeloid dendritic cells) exhibit a tolerogenic phenotype, despite constant exposure to danger signals from food and microbes. This reduces the induction of pro‐inflammatory immune responses leading to systemic allergic reactions. Oral tissues contain relatively few mast cells and eosinophils (mostly located in submucosal areas) and, in comparison with subcutaneous tissue, are less likely to give rise to anaphylactic reactions. SLIT‐associated immune responses include the induction of circulating, allergen‐specific Th1 and regulatory CD4+ T cells, leading to clinical tolerance. Although 40–75% of patients receiving SLIT experience mild, transient local reactions in the oral mucosa, these primary reactions rarely necessitate dose reduction or treatment interruption. We discuss 11 published case reports of anaphylaxis (all nonfatal) diagnosed according to the World Allergy Organization criteria and relate this figure to the approximately 1 billion SLIT doses administered worldwide since 2000. Anaphylaxis risk factors associated with SCIT and/or SLIT should be characterized further." @default.
• W1567449627 created "2016-06-24" @default.
• W1567449627 creator A5014470416 @default.
• W1567449627 creator A5025157783 @default.
• W1567449627 creator A5064146791 @default.
• W1567449627 creator A5070803984 @default.
• W1567449627 creator A5079964062 @default.
• W1567449627 creator A5087600572 @default.
• W1567449627 date "2011-12-12" @default.
• W1567449627 modified "2023-10-18" @default.
• W1567449627 title "Sublingual allergen immunotherapy: mode of action and its relationship with the safety profile" @default.
• W1567449627 cites W1606710553 @default.
• W1567449627 cites W1608960808 @default.
• W1567449627 cites W1831654756 @default.
• W1567449627 cites W1963911570 @default.
• W1567449627 cites W1993375385 @default.
• W1567449627 cites W1996904229 @default.
• W1567449627 cites W2011079863 @default.
• W1567449627 cites W2015322930 @default.
• W1567449627 cites W2017616532 @default.
• W1567449627 cites W2018589247 @default.
• W1567449627 cites W2020507548 @default.
• W1567449627 cites W2021490046 @default.
• W1567449627 cites W2022844594 @default.
• W1567449627 cites W2024757690 @default.
• W1567449627 cites W2032982186 @default.
• W1567449627 cites W2037178393 @default.
• W1567449627 cites W2040547148 @default.
• W1567449627 cites W2041703033 @default.
• W1567449627 cites W2044792690 @default.
• W1567449627 cites W2051712616 @default.
• W1567449627 cites W2052278810 @default.
• W1567449627 cites W2052951012 @default.
• W1567449627 cites W2065738222 @default.
• W1567449627 cites W2071814570 @default.
• W1567449627 cites W2073317010 @default.
• W1567449627 cites W2080147488 @default.
• W1567449627 cites W2082346168 @default.
• W1567449627 cites W2091258962 @default.
• W1567449627 cites W2102869202 @default.
• W1567449627 cites W2114501738 @default.
• W1567449627 cites W2114743889 @default.
• W1567449627 cites W2116810696 @default.
• W1567449627 cites W2121760095 @default.
• W1567449627 cites W2125803815 @default.
• W1567449627 cites W2127698353 @default.
• W1567449627 cites W2134575877 @default.
• W1567449627 cites W2162467363 @default.
• W1567449627 cites W2164132449 @default.
• W1567449627 doi "https://doi.org/10.1111/j.1398-9995.2011.02761.x" @default.
• W1567449627 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22150126" @default.
• W1567449627 hasPublicationYear "2011" @default.
• W1567449627 type Work @default.
• W1567449627 sameAs 1567449627 @default.
• W1567449627 citedByCount "233" @default.
• W1567449627 countsByYear W15674496272012 @default.
• W1567449627 countsByYear W15674496272013 @default.
• W1567449627 countsByYear W15674496272014 @default.
• W1567449627 countsByYear W15674496272015 @default.
• W1567449627 countsByYear W15674496272016 @default.
• W1567449627 countsByYear W15674496272017 @default.
• W1567449627 countsByYear W15674496272018 @default.
• W1567449627 countsByYear W15674496272019 @default.
• W1567449627 countsByYear W15674496272020 @default.
• W1567449627 countsByYear W15674496272021 @default.
• W1567449627 countsByYear W15674496272022 @default.
• W1567449627 countsByYear W15674496272023 @default.
• W1567449627 crossrefType "journal-article" @default.
• W1567449627 hasAuthorship W1567449627A5014470416 @default.
• W1567449627 hasAuthorship W1567449627A5025157783 @default.
• W1567449627 hasAuthorship W1567449627A5064146791 @default.
• W1567449627 hasAuthorship W1567449627A5070803984 @default.
• W1567449627 hasAuthorship W1567449627A5079964062 @default.
• W1567449627 hasAuthorship W1567449627A5087600572 @default.
• W1567449627 hasBestOaLocation W15674496271 @default.
• W1567449627 hasConcept C199215989 @default.
• W1567449627 hasConcept C203014093 @default.
• W1567449627 hasConcept C207480886 @default.
• W1567449627 hasConcept C2775933838 @default.
• W1567449627 hasConcept C2777701055 @default.
• W1567449627 hasConcept C2779787640 @default.
• W1567449627 hasConcept C2780510475 @default.
• W1567449627 hasConcept C54355233 @default.
• W1567449627 hasConcept C71924100 @default.
• W1567449627 hasConcept C86803240 @default.
• W1567449627 hasConcept C8891405 @default.
• W1567449627 hasConceptScore W1567449627C199215989 @default.
• W1567449627 hasConceptScore W1567449627C203014093 @default.
• W1567449627 hasConceptScore W1567449627C207480886 @default.
• W1567449627 hasConceptScore W1567449627C2775933838 @default.
• W1567449627 hasConceptScore W1567449627C2777701055 @default.
• W1567449627 hasConceptScore W1567449627C2779787640 @default.
• W1567449627 hasConceptScore W1567449627C2780510475 @default.
• W1567449627 hasConceptScore W1567449627C54355233 @default.
• W1567449627 hasConceptScore W1567449627C71924100 @default.
• W1567449627 hasConceptScore W1567449627C86803240 @default.
• W1567449627 hasConceptScore W1567449627C8891405 @default.
• W1567449627 hasIssue "3" @default.

• next