FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567486735> ?p ?o ?g. }

• W1567486735 endingPage "559" @default.
• W1567486735 startingPage "547" @default.
• W1567486735 abstract "Chronic exposure to stress has been implicated in physical and mental illness, and such experiences can produce alterations in the connectivity and number of neurones within the brain to variations in the expression of specific genes. The purpose of this study was to determine how repeated exposure to social defeat affects neuronal activation patterns within the male Syrian hamster brain. Toward this end, the levels c‐ fos mRNA were compared among three groups: (1) handled controls (HC); (2) acutely defeated males (AD); and (3) chronically defeated males (15 min aggression daily, 7 days) exposed to an acute challenge (CD). Plasma glucocorticoids were also measured and compared among groups as an index of neuroendocrine activity. The results show a selective pattern of habituation of immediate early gene expression within the brains of chronically defeated males. In particular, c‐ fos mRNA levels were significantly decreased within the paraventricular nucleus of the hypothalamus (PVN), supraoptic nucleus of the hypothalamus, septohypothalamic nucleus, intermediate subdivision of the lateral septum, central amygdaloid nucleus, and the amygdalohippocampal area in the CD group exposed to an acute challenge when compared to males defeated only once. In contrast, c‐ fos expression within the anterior and ventromedial nuclei of the hypothalamus, dorsal periaqueductal grey, dorsal raphe, cuneiform nucleus, and locus coeruleus did not differ between AD and CD groups. Similarly, plasma levels of cortisol and corticosterone in CD group were equivalent to those observed after a single defeat experience. We discuss the possibility that decreased expression of c‐ fos mRNA within the PVN and other brain regions of defeated animals–in the presence of elevated adrenal steroids–may reflect a state of molecular plasticity that could alter neurotransmission within the limbic‐hypothalamo‐pituitary‐adrenocortical axis. In contrast, brain areas that maintain relatively high levels of c‐ fos mRNA following repeated defeat may reflect processes less likely to adapt such as defensive behaviour." @default.
• W1567486735 created "2016-06-24" @default.
• W1567486735 creator A5007964297 @default.
• W1567486735 creator A5045189334 @default.
• W1567486735 creator A5049121567 @default.
• W1567486735 creator A5049286080 @default.
• W1567486735 date "1999-07-01" @default.
• W1567486735 modified "2023-10-16" @default.
• W1567486735 title "Differential Expression of c‐<i>fos</i> mRNA Within Neurocircuits of Male Hamsters Exposed to Acute or Chronic Defeat" @default.
• W1567486735 cites W1535894955 @default.
• W1567486735 cites W1553476847 @default.
• W1567486735 cites W1589734479 @default.
• W1567486735 cites W1967318820 @default.
• W1567486735 cites W1967569415 @default.
• W1567486735 cites W1974533702 @default.
• W1567486735 cites W1978803611 @default.
• W1567486735 cites W1979424682 @default.
• W1567486735 cites W1982835526 @default.
• W1567486735 cites W1989851738 @default.
• W1567486735 cites W1991201649 @default.
• W1567486735 cites W1991954368 @default.
• W1567486735 cites W2000038072 @default.
• W1567486735 cites W2000338336 @default.
• W1567486735 cites W2001280087 @default.
• W1567486735 cites W2006143515 @default.
• W1567486735 cites W2021705632 @default.
• W1567486735 cites W2022860464 @default.
• W1567486735 cites W2022951599 @default.
• W1567486735 cites W2028318252 @default.
• W1567486735 cites W2028588306 @default.
• W1567486735 cites W2029741047 @default.
• W1567486735 cites W2030231550 @default.
• W1567486735 cites W2030745669 @default.
• W1567486735 cites W2031970793 @default.
• W1567486735 cites W2033313592 @default.
• W1567486735 cites W2037043198 @default.
• W1567486735 cites W2044258305 @default.
• W1567486735 cites W2045798063 @default.
• W1567486735 cites W2046027487 @default.
• W1567486735 cites W2047919057 @default.
• W1567486735 cites W2055096048 @default.
• W1567486735 cites W2056249673 @default.
• W1567486735 cites W2056301492 @default.
• W1567486735 cites W2056503984 @default.
• W1567486735 cites W2056847743 @default.
• W1567486735 cites W2058907445 @default.
• W1567486735 cites W2067952794 @default.
• W1567486735 cites W2068712780 @default.
• W1567486735 cites W2078046758 @default.
• W1567486735 cites W2082575561 @default.
• W1567486735 cites W2092060676 @default.
• W1567486735 cites W2093710529 @default.
• W1567486735 cites W2094790033 @default.
• W1567486735 cites W2095395905 @default.
• W1567486735 cites W2111225560 @default.
• W1567486735 cites W2111431369 @default.
• W1567486735 cites W2112211792 @default.
• W1567486735 cites W2121061650 @default.
• W1567486735 cites W2127090550 @default.
• W1567486735 cites W2154760725 @default.
• W1567486735 cites W4255593113 @default.
• W1567486735 cites W4292291195 @default.
• W1567486735 cites W4300172940 @default.
• W1567486735 cites W793331764 @default.
• W1567486735 doi "https://doi.org/10.1046/j.1365-2826.1999.00354.x" @default.
• W1567486735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10444312" @default.
• W1567486735 hasPublicationYear "1999" @default.
• W1567486735 type Work @default.
• W1567486735 sameAs 1567486735 @default.
• W1567486735 citedByCount "105" @default.
• W1567486735 countsByYear W15674867352012 @default.
• W1567486735 countsByYear W15674867352013 @default.
• W1567486735 countsByYear W15674867352014 @default.
• W1567486735 countsByYear W15674867352015 @default.
• W1567486735 countsByYear W15674867352016 @default.
• W1567486735 countsByYear W15674867352017 @default.
• W1567486735 countsByYear W15674867352018 @default.
• W1567486735 countsByYear W15674867352019 @default.
• W1567486735 countsByYear W15674867352020 @default.
• W1567486735 countsByYear W15674867352021 @default.
• W1567486735 countsByYear W15674867352022 @default.
• W1567486735 countsByYear W15674867352023 @default.
• W1567486735 crossrefType "journal-article" @default.
• W1567486735 hasAuthorship W1567486735A5007964297 @default.
• W1567486735 hasAuthorship W1567486735A5045189334 @default.
• W1567486735 hasAuthorship W1567486735A5049121567 @default.
• W1567486735 hasAuthorship W1567486735A5049286080 @default.
• W1567486735 hasBestOaLocation W15674867352 @default.
• W1567486735 hasConcept C104317684 @default.
• W1567486735 hasConcept C126322002 @default.
• W1567486735 hasConcept C134018914 @default.
• W1567486735 hasConcept C150194340 @default.
• W1567486735 hasConcept C169760540 @default.
• W1567486735 hasConcept C170493617 @default.
• W1567486735 hasConcept C2775864247 @default.
• W1567486735 hasConcept C2776046087 @default.
• W1567486735 hasConcept C2776370428 @default.
• W1567486735 hasConcept C2776552330 @default.

• next