Matches in SemOpenAlex for { <https://semopenalex.org/work/W156749682> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W156749682 endingPage "57" @default.
- W156749682 startingPage "47" @default.
- W156749682 abstract "Peripheral nerve injuries are an economic burden for society in general and despite advanced microsurgical reconstruction of the damaged nerves the functional result is unsatisfactory with poor sensory recovery and reduced motor functions (Wiberg and Terenghi, Surg Technol Int 11:303-310, 2003). In the treatment of nerve injuries transplantation of a nerve graft is often necessary, especially in nerve gap injuries.Schwann cells (SC) are the key facilitators of peripheral nerve regeneration and are responsible for the formation and maintenance of the myelin sheath around axons in peripheral nerve fibers. They are essential for nerve regeneration after nerve injuries as they produce extracellular matrix molecules, integrins, and trophic factors providing guidance and trophic support for regenerating axons (Wiberg and Terenghi, Surg Technol Int 11:303-310, 2003; Bunge, J Neurol 242:S19-21, 1994; Ide, Neurosci Res 25:101-121, 1996; Mahanthappa et al. J Neurosci 16:4673-4683, 1996). However, the use of ex vivo cultured SC within conduits is limited in its clinical application because of the concomitant donor site morbidity and the slow growth of these cells in vitro (Tohill et al. Tissue Eng 10:1359-1367, 2004).Mesenchymal stem cells (MSC or bone marrow stromal cells) and adipose-derived stem cells (ASC) are easily accessible non-hematopoietic stem cells that have proven essential for research purposes due to their plasticity and ability to differentiate into several functional cell types. This alternative source of cells is relatively simple to isolate and expand in culture. We have demonstrated that MSC and ASC can trans-differentiate along a SC lineage with functional properties and growth factor synthesis activities similar to those of native SC and could provide nerve fiber support and guidance during nerve regeneration." @default.
- W156749682 created "2016-06-24" @default.
- W156749682 creator A5037217541 @default.
- W156749682 creator A5078592160 @default.
- W156749682 creator A5082599655 @default.
- W156749682 date "2012-01-01" @default.
- W156749682 modified "2023-10-18" @default.
- W156749682 title "Isolation of Adult Stem Cells and Their Differentiation to Schwann Cells" @default.
- W156749682 cites W1968442155 @default.
- W156749682 cites W1977243716 @default.
- W156749682 cites W1991415492 @default.
- W156749682 cites W2003155683 @default.
- W156749682 cites W2003637620 @default.
- W156749682 cites W2006811526 @default.
- W156749682 cites W2020620728 @default.
- W156749682 cites W2032281007 @default.
- W156749682 cites W2059066863 @default.
- W156749682 cites W2064219974 @default.
- W156749682 cites W2066135105 @default.
- W156749682 cites W2069006548 @default.
- W156749682 cites W2095257528 @default.
- W156749682 cites W2102638899 @default.
- W156749682 cites W2105252992 @default.
- W156749682 cites W2115062578 @default.
- W156749682 cites W2118970991 @default.
- W156749682 cites W2134806200 @default.
- W156749682 cites W2137381294 @default.
- W156749682 cites W2142410730 @default.
- W156749682 cites W2148841089 @default.
- W156749682 cites W2149996379 @default.
- W156749682 cites W2158330548 @default.
- W156749682 cites W2159999899 @default.
- W156749682 cites W2166724945 @default.
- W156749682 doi "https://doi.org/10.1007/978-1-61779-980-8_5" @default.
- W156749682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22914932" @default.
- W156749682 hasPublicationYear "2012" @default.
- W156749682 type Work @default.
- W156749682 sameAs 156749682 @default.
- W156749682 citedByCount "24" @default.
- W156749682 countsByYear W1567496822013 @default.
- W156749682 countsByYear W1567496822014 @default.
- W156749682 countsByYear W1567496822015 @default.
- W156749682 countsByYear W1567496822017 @default.
- W156749682 countsByYear W1567496822018 @default.
- W156749682 countsByYear W1567496822019 @default.
- W156749682 countsByYear W1567496822020 @default.
- W156749682 countsByYear W1567496822021 @default.
- W156749682 countsByYear W1567496822022 @default.
- W156749682 crossrefType "book-chapter" @default.
- W156749682 hasAuthorship W156749682A5037217541 @default.
- W156749682 hasAuthorship W156749682A5078592160 @default.
- W156749682 hasAuthorship W156749682A5082599655 @default.
- W156749682 hasConcept C105702510 @default.
- W156749682 hasConcept C136940099 @default.
- W156749682 hasConcept C142724271 @default.
- W156749682 hasConcept C16930146 @default.
- W156749682 hasConcept C169760540 @default.
- W156749682 hasConcept C171056886 @default.
- W156749682 hasConcept C198826908 @default.
- W156749682 hasConcept C2776880756 @default.
- W156749682 hasConcept C2780007613 @default.
- W156749682 hasConcept C28328180 @default.
- W156749682 hasConcept C71924100 @default.
- W156749682 hasConcept C86803240 @default.
- W156749682 hasConcept C95444343 @default.
- W156749682 hasConceptScore W156749682C105702510 @default.
- W156749682 hasConceptScore W156749682C136940099 @default.
- W156749682 hasConceptScore W156749682C142724271 @default.
- W156749682 hasConceptScore W156749682C16930146 @default.
- W156749682 hasConceptScore W156749682C169760540 @default.
- W156749682 hasConceptScore W156749682C171056886 @default.
- W156749682 hasConceptScore W156749682C198826908 @default.
- W156749682 hasConceptScore W156749682C2776880756 @default.
- W156749682 hasConceptScore W156749682C2780007613 @default.
- W156749682 hasConceptScore W156749682C28328180 @default.
- W156749682 hasConceptScore W156749682C71924100 @default.
- W156749682 hasConceptScore W156749682C86803240 @default.
- W156749682 hasConceptScore W156749682C95444343 @default.
- W156749682 hasLocation W1567496821 @default.
- W156749682 hasLocation W1567496822 @default.
- W156749682 hasOpenAccess W156749682 @default.
- W156749682 hasPrimaryLocation W1567496821 @default.
- W156749682 hasRelatedWork W2035886436 @default.
- W156749682 hasRelatedWork W2038751426 @default.
- W156749682 hasRelatedWork W2057686645 @default.
- W156749682 hasRelatedWork W2064960282 @default.
- W156749682 hasRelatedWork W2332201957 @default.
- W156749682 hasRelatedWork W2382901884 @default.
- W156749682 hasRelatedWork W2736089592 @default.
- W156749682 hasRelatedWork W4304822906 @default.
- W156749682 hasRelatedWork W4365444270 @default.
- W156749682 hasRelatedWork W2581823235 @default.
- W156749682 isParatext "false" @default.
- W156749682 isRetracted "false" @default.
- W156749682 magId "156749682" @default.
- W156749682 workType "book-chapter" @default.