Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567505077> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1567505077 endingPage "19318" @default.
- W1567505077 startingPage "19312" @default.
- W1567505077 abstract "Glutaraldehyde-fixed membranes from rabbit kidney cortex were used to characterize binding of monomeric adenosine deaminase to the adenosine deaminase complexing protein. With the use of bovine adenosine deaminase it was shown that enzyme binding is a saturable, high affinity process. The K value for binding of the bovine enzyme was 11 nM. Maximum enzyme binding and rate of binding to a constant amount of membrane did not vary significantly from pH 5.0 to 9.5. Metal ions, with the exception of Hg2+, sulfhydryl reagents, and other proteins had little or a slightly stimulatory effect on maximum binding. Mercuric ion inhibited binding. Using biotinylated bovine adenosine deaminase it was shown that purified rabbit, human, and monkey enzymes compete for binding sites on fixed membranes. The K values for the rabbit and human enzymes were 9 and 6 nM, respectively. Mouse or guinea pig adenosine deaminase did not bind to the membranes or compete with the biotinylated bovine enzyme for binding sites. The retention of characteristics required for binding by enzymes from rabbit, human, monkey, and calf tissues argues for biologic significance of the adenosine deaminase-complexing protein interaction. The basis for the apparent failure of rodent adenosine deaminase to bind to complexing protein remains to be determined." @default.
- W1567505077 created "2016-06-24" @default.
- W1567505077 creator A5041198951 @default.
- W1567505077 creator A5052800851 @default.
- W1567505077 creator A5062223007 @default.
- W1567505077 creator A5087542378 @default.
- W1567505077 date "1990-11-01" @default.
- W1567505077 modified "2023-09-27" @default.
- W1567505077 title "Characterization of the adenosine deaminase-adenosine deaminase complexing protein binding reaction." @default.
- W1567505077 cites W1488263217 @default.
- W1567505077 cites W1490127649 @default.
- W1567505077 cites W1490621345 @default.
- W1567505077 cites W1493147966 @default.
- W1567505077 cites W1509003053 @default.
- W1567505077 cites W1513969749 @default.
- W1567505077 cites W1540947399 @default.
- W1567505077 cites W1563968609 @default.
- W1567505077 cites W1598024033 @default.
- W1567505077 cites W1625660792 @default.
- W1567505077 cites W1632628366 @default.
- W1567505077 cites W1775749144 @default.
- W1567505077 cites W1963994758 @default.
- W1567505077 cites W1967123959 @default.
- W1567505077 cites W1986248021 @default.
- W1567505077 cites W1991869406 @default.
- W1567505077 cites W2006857292 @default.
- W1567505077 cites W2008908943 @default.
- W1567505077 cites W2014568792 @default.
- W1567505077 cites W2021108968 @default.
- W1567505077 cites W2028307671 @default.
- W1567505077 cites W2046428669 @default.
- W1567505077 cites W208281678 @default.
- W1567505077 cites W2084250810 @default.
- W1567505077 cites W2085354367 @default.
- W1567505077 cites W2085997537 @default.
- W1567505077 cites W2098924542 @default.
- W1567505077 cites W2100770709 @default.
- W1567505077 cites W21039076 @default.
- W1567505077 cites W2111301002 @default.
- W1567505077 cites W2111817213 @default.
- W1567505077 cites W2474389999 @default.
- W1567505077 cites W75946240 @default.
- W1567505077 cites W2003290637 @default.
- W1567505077 doi "https://doi.org/10.1016/s0021-9258(17)30659-2" @default.
- W1567505077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2121737" @default.
- W1567505077 hasPublicationYear "1990" @default.
- W1567505077 type Work @default.
- W1567505077 sameAs 1567505077 @default.
- W1567505077 citedByCount "42" @default.
- W1567505077 countsByYear W15675050772012 @default.
- W1567505077 countsByYear W15675050772013 @default.
- W1567505077 countsByYear W15675050772015 @default.
- W1567505077 countsByYear W15675050772017 @default.
- W1567505077 countsByYear W15675050772020 @default.
- W1567505077 countsByYear W15675050772021 @default.
- W1567505077 crossrefType "journal-article" @default.
- W1567505077 hasAuthorship W1567505077A5041198951 @default.
- W1567505077 hasAuthorship W1567505077A5052800851 @default.
- W1567505077 hasAuthorship W1567505077A5062223007 @default.
- W1567505077 hasAuthorship W1567505077A5087542378 @default.
- W1567505077 hasBestOaLocation W15675050771 @default.
- W1567505077 hasConcept C165912504 @default.
- W1567505077 hasConcept C185592680 @default.
- W1567505077 hasConcept C2776991684 @default.
- W1567505077 hasConcept C34628245 @default.
- W1567505077 hasConcept C55493867 @default.
- W1567505077 hasConceptScore W1567505077C165912504 @default.
- W1567505077 hasConceptScore W1567505077C185592680 @default.
- W1567505077 hasConceptScore W1567505077C2776991684 @default.
- W1567505077 hasConceptScore W1567505077C34628245 @default.
- W1567505077 hasConceptScore W1567505077C55493867 @default.
- W1567505077 hasIssue "31" @default.
- W1567505077 hasLocation W15675050771 @default.
- W1567505077 hasOpenAccess W1567505077 @default.
- W1567505077 hasPrimaryLocation W15675050771 @default.
- W1567505077 hasRelatedWork W1498415432 @default.
- W1567505077 hasRelatedWork W1546024790 @default.
- W1567505077 hasRelatedWork W1971449617 @default.
- W1567505077 hasRelatedWork W1997018617 @default.
- W1567505077 hasRelatedWork W2016119250 @default.
- W1567505077 hasRelatedWork W2059891292 @default.
- W1567505077 hasRelatedWork W2265341525 @default.
- W1567505077 hasRelatedWork W2415089212 @default.
- W1567505077 hasRelatedWork W2972560238 @default.
- W1567505077 hasRelatedWork W2186865991 @default.
- W1567505077 hasVolume "265" @default.
- W1567505077 isParatext "false" @default.
- W1567505077 isRetracted "false" @default.
- W1567505077 magId "1567505077" @default.
- W1567505077 workType "article" @default.