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• W1567508270 abstract "Hepatic encephalopathy (HE) is a common complication of cirrhosis, leading to frequent hospitalizations. Because ammonia is thought to play an important role in the pathogenesis of HE, therapies specifically aimed at reducing ammonia levels have been developed for conditions causing hyperammonemia, including HE. Ammonia scavengers have been used in HE patients, leading to improvements in symptoms. Bowel cleansing with polyethylene glycol has also been studied recently, resulting in more rapid improvement in acute HE compared with lactulose. Extracorporeal devices have been used in cases of refractory HE but currently are used primarily in research settings and not approved for clinical management for HE." @default.
• W1567508270 created "2016-06-24" @default.
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• W1567508270 date "2015-08-01" @default.
• W1567508270 modified "2023-10-16" @default.
• W1567508270 title "Novel Ammonia-Lowering Agents for Hepatic Encephalopathy" @default.
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• W1567508270 doi "https://doi.org/10.1016/j.cld.2015.04.008" @default.
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