FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567541371> ?p ?o ?g. }

• W1567541371 endingPage "591" @default.
• W1567541371 startingPage "580" @default.
• W1567541371 abstract "In Crohn’s disease bacteria could be detected in the adjacent mesenteric fat characterized by hypertrophy of unknown function. This study aimed to define effector responses of this compartment induced by bacterial translocation during intestinal inflammation. Dextran sulfate sodium-induced colitis served as a model of intestinal inflammation. Translocation of peptides and bacteria into mesenteric fat was evaluated. Innate functions of mesenteric fat and epithelium were characterized at whole tissue, cellular, and effector molecule levels. Orally applied peptides translocated in healthy wild-type (WT) mice. Bacterial translocation was not detected in healthy and acute but increased in chronic colitis. Mesenteric fat from colitic mice released elevated levels of cytokines and was infiltrated by immune cells. In MyD88−/− mice bacterial translocation occurred in health and increased in colitis. The exaggerated cytokine production in mesenteric fat accompanying colonic inflammation in WT mice was less distinct in MyD88−/− mice. In vitro studies revealed that fat not only increases cytokine production following contact with bacterial products, but also that preadipocytes are potent phagocytes. Colonic inflammation is accompanied by massive cytokine production and immune cell infiltration in adjacent adipose tissue. These effects can be considered as protective mechanisms of the mesenteric fat in the defense of bacterial translocation." @default.
• W1567541371 created "2016-06-24" @default.
• W1567541371 creator A5004519347 @default.
• W1567541371 creator A5008770927 @default.
• W1567541371 creator A5009959860 @default.
• W1567541371 creator A5016750114 @default.
• W1567541371 creator A5018044368 @default.
• W1567541371 creator A5018180535 @default.
• W1567541371 creator A5022252584 @default.
• W1567541371 creator A5027633664 @default.
• W1567541371 creator A5029305848 @default.
• W1567541371 creator A5031092899 @default.
• W1567541371 creator A5031972677 @default.
• W1567541371 creator A5034039610 @default.
• W1567541371 creator A5052150456 @default.
• W1567541371 creator A5056103726 @default.
• W1567541371 creator A5089930328 @default.
• W1567541371 date "2012-09-01" @default.
• W1567541371 modified "2023-10-18" @default.
• W1567541371 title "Mesenteric fat—control site for bacterial translocation in colitis?" @default.
• W1567541371 cites W1556864263 @default.
• W1567541371 cites W1576984763 @default.
• W1567541371 cites W1590709474 @default.
• W1567541371 cites W1969260603 @default.
• W1567541371 cites W1981444875 @default.
• W1567541371 cites W1981759538 @default.
• W1567541371 cites W1985672713 @default.
• W1567541371 cites W1996120614 @default.
• W1567541371 cites W2005276831 @default.
• W1567541371 cites W2009381049 @default.
• W1567541371 cites W2023343969 @default.
• W1567541371 cites W2037565352 @default.
• W1567541371 cites W2042884029 @default.
• W1567541371 cites W2046208657 @default.
• W1567541371 cites W2055877369 @default.
• W1567541371 cites W2061681190 @default.
• W1567541371 cites W2065205410 @default.
• W1567541371 cites W2076092609 @default.
• W1567541371 cites W2079214938 @default.
• W1567541371 cites W2081931036 @default.
• W1567541371 cites W2083089709 @default.
• W1567541371 cites W2085408028 @default.
• W1567541371 cites W2089783517 @default.
• W1567541371 cites W2090631845 @default.
• W1567541371 cites W2095731887 @default.
• W1567541371 cites W2101328621 @default.
• W1567541371 cites W2103459268 @default.
• W1567541371 cites W2104442443 @default.
• W1567541371 cites W2106694537 @default.
• W1567541371 cites W2111648036 @default.
• W1567541371 cites W2114868173 @default.
• W1567541371 cites W2119519672 @default.
• W1567541371 cites W2125249450 @default.
• W1567541371 cites W2131432706 @default.
• W1567541371 cites W2152213080 @default.
• W1567541371 cites W2153905079 @default.
• W1567541371 cites W2163524675 @default.
• W1567541371 cites W2164157052 @default.
• W1567541371 cites W2166626624 @default.
• W1567541371 cites W2169424849 @default.
• W1567541371 cites W2169479471 @default.
• W1567541371 cites W2169909966 @default.
• W1567541371 cites W2197555561 @default.
• W1567541371 cites W2313205252 @default.
• W1567541371 cites W4249727000 @default.
• W1567541371 cites W4312243406 @default.
• W1567541371 doi "https://doi.org/10.1038/mi.2012.33" @default.
• W1567541371 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22569302" @default.
• W1567541371 hasPublicationYear "2012" @default.
• W1567541371 type Work @default.
• W1567541371 sameAs 1567541371 @default.
• W1567541371 citedByCount "61" @default.
• W1567541371 countsByYear W15675413712013 @default.
• W1567541371 countsByYear W15675413712014 @default.
• W1567541371 countsByYear W15675413712015 @default.
• W1567541371 countsByYear W15675413712016 @default.
• W1567541371 countsByYear W15675413712017 @default.
• W1567541371 countsByYear W15675413712018 @default.
• W1567541371 countsByYear W15675413712019 @default.
• W1567541371 countsByYear W15675413712020 @default.
• W1567541371 countsByYear W15675413712021 @default.
• W1567541371 countsByYear W15675413712022 @default.
• W1567541371 countsByYear W15675413712023 @default.
• W1567541371 crossrefType "journal-article" @default.
• W1567541371 hasAuthorship W1567541371A5004519347 @default.
• W1567541371 hasAuthorship W1567541371A5008770927 @default.
• W1567541371 hasAuthorship W1567541371A5009959860 @default.
• W1567541371 hasAuthorship W1567541371A5016750114 @default.
• W1567541371 hasAuthorship W1567541371A5018044368 @default.
• W1567541371 hasAuthorship W1567541371A5018180535 @default.
• W1567541371 hasAuthorship W1567541371A5022252584 @default.
• W1567541371 hasAuthorship W1567541371A5027633664 @default.
• W1567541371 hasAuthorship W1567541371A5029305848 @default.
• W1567541371 hasAuthorship W1567541371A5031092899 @default.
• W1567541371 hasAuthorship W1567541371A5031972677 @default.
• W1567541371 hasAuthorship W1567541371A5034039610 @default.
• W1567541371 hasAuthorship W1567541371A5052150456 @default.
• W1567541371 hasAuthorship W1567541371A5056103726 @default.

• next