Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567643829> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1567643829 endingPage "285" @default.
- W1567643829 startingPage "285" @default.
- W1567643829 abstract "Polyoma virus-associated nephropathy is an increasingly recognized cause of graft dysfunction among kidney transplant recipients and could be the result of use of potent immunosuppression following transplantation. Because there is no safe and effective anti-viral therapy available presently, screening-based prevention and pre-emptive strategy are recommended. This study, which was conducted at the Nephrology Unit, Internal Medicine Department, Alexandria University, consisted of two phases: Phase 1 was a cross-sectional study and phase 2 was a 6-month follow-up study only for polyoma virus-positive cases. Phase 1 included 75 renal allograft recipients from living donors. Urine cytology for decoy cells and quantitative real-time blood polymerase chain reaction (PCR) for the BK virus (BKV) were performed on all the study patients. Renal biopsy was performed only in patients with deteriorating renal function associated with positive urine cytology. Patients who showed positive urine cytology for decoy cells and/or positive quantitative BKV PCR assay were followed-up for six months. During follow-up, the serum creatinine level, with or without urine cytology for decoy cells, and BKV PCR viral load assay were performed. Among the 75 kidney transplant recipients studied, eight were positive for decoy cells (11%), three showed viremia by quantitative PCR for BKV (4.1%), while two others showed nephropathy (2.7%) in the form of tubulointerstitial nephritis with intra-nuclear inclusions in the tubular cells. Cases with stable renal function and positive decoy cells or viremia cleared the virus spontaneously during follow-up without any intervention. Only one case with biopsyproven nephropathy and deteriorating graft function, with undetectable BKV in blood, lost the graft while another case with viremia died during follow-up due to septicemia. Our study suggests that polyoma virus should be considered as a cause of nephropathy in renal transplant recipients. Further research is required to understand this entity better." @default.
- W1567643829 created "2016-06-24" @default.
- W1567643829 creator A5000902483 @default.
- W1567643829 creator A5037386102 @default.
- W1567643829 creator A5052705269 @default.
- W1567643829 creator A5054684703 @default.
- W1567643829 creator A5084462618 @default.
- W1567643829 date "2014-01-01" @default.
- W1567643829 modified "2023-09-26" @default.
- W1567643829 title "Occurrence of the polyomavirus among kidney transplant recipients: A single-center study" @default.
- W1567643829 doi "https://doi.org/10.4103/1319-2442.128509" @default.
- W1567643829 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24625993" @default.
- W1567643829 hasPublicationYear "2014" @default.
- W1567643829 type Work @default.
- W1567643829 sameAs 1567643829 @default.
- W1567643829 citedByCount "3" @default.
- W1567643829 countsByYear W15676438292016 @default.
- W1567643829 countsByYear W15676438292017 @default.
- W1567643829 crossrefType "journal-article" @default.
- W1567643829 hasAuthorship W1567643829A5000902483 @default.
- W1567643829 hasAuthorship W1567643829A5037386102 @default.
- W1567643829 hasAuthorship W1567643829A5052705269 @default.
- W1567643829 hasAuthorship W1567643829A5054684703 @default.
- W1567643829 hasAuthorship W1567643829A5084462618 @default.
- W1567643829 hasBestOaLocation W15676438291 @default.
- W1567643829 hasConcept C121608353 @default.
- W1567643829 hasConcept C126322002 @default.
- W1567643829 hasConcept C134018914 @default.
- W1567643829 hasConcept C142724271 @default.
- W1567643829 hasConcept C159641895 @default.
- W1567643829 hasConcept C18823058 @default.
- W1567643829 hasConcept C203014093 @default.
- W1567643829 hasConcept C2522874641 @default.
- W1567643829 hasConcept C2776185481 @default.
- W1567643829 hasConcept C2777548846 @default.
- W1567643829 hasConcept C2778199330 @default.
- W1567643829 hasConcept C2780026642 @default.
- W1567643829 hasConcept C2780091579 @default.
- W1567643829 hasConcept C2780252810 @default.
- W1567643829 hasConcept C2780303639 @default.
- W1567643829 hasConcept C2780352672 @default.
- W1567643829 hasConcept C2781184683 @default.
- W1567643829 hasConcept C2911091166 @default.
- W1567643829 hasConcept C54847362 @default.
- W1567643829 hasConcept C555293320 @default.
- W1567643829 hasConcept C71924100 @default.
- W1567643829 hasConcept C90924648 @default.
- W1567643829 hasConceptScore W1567643829C121608353 @default.
- W1567643829 hasConceptScore W1567643829C126322002 @default.
- W1567643829 hasConceptScore W1567643829C134018914 @default.
- W1567643829 hasConceptScore W1567643829C142724271 @default.
- W1567643829 hasConceptScore W1567643829C159641895 @default.
- W1567643829 hasConceptScore W1567643829C18823058 @default.
- W1567643829 hasConceptScore W1567643829C203014093 @default.
- W1567643829 hasConceptScore W1567643829C2522874641 @default.
- W1567643829 hasConceptScore W1567643829C2776185481 @default.
- W1567643829 hasConceptScore W1567643829C2777548846 @default.
- W1567643829 hasConceptScore W1567643829C2778199330 @default.
- W1567643829 hasConceptScore W1567643829C2780026642 @default.
- W1567643829 hasConceptScore W1567643829C2780091579 @default.
- W1567643829 hasConceptScore W1567643829C2780252810 @default.
- W1567643829 hasConceptScore W1567643829C2780303639 @default.
- W1567643829 hasConceptScore W1567643829C2780352672 @default.
- W1567643829 hasConceptScore W1567643829C2781184683 @default.
- W1567643829 hasConceptScore W1567643829C2911091166 @default.
- W1567643829 hasConceptScore W1567643829C54847362 @default.
- W1567643829 hasConceptScore W1567643829C555293320 @default.
- W1567643829 hasConceptScore W1567643829C71924100 @default.
- W1567643829 hasConceptScore W1567643829C90924648 @default.
- W1567643829 hasIssue "2" @default.
- W1567643829 hasLocation W15676438291 @default.
- W1567643829 hasLocation W15676438292 @default.
- W1567643829 hasLocation W15676438293 @default.
- W1567643829 hasOpenAccess W1567643829 @default.
- W1567643829 hasPrimaryLocation W15676438291 @default.
- W1567643829 hasRelatedWork W1995540881 @default.
- W1567643829 hasRelatedWork W2035043466 @default.
- W1567643829 hasRelatedWork W2053074936 @default.
- W1567643829 hasRelatedWork W2064419749 @default.
- W1567643829 hasRelatedWork W2086347861 @default.
- W1567643829 hasRelatedWork W2379243897 @default.
- W1567643829 hasRelatedWork W2588128012 @default.
- W1567643829 hasRelatedWork W2913029142 @default.
- W1567643829 hasRelatedWork W3032593084 @default.
- W1567643829 hasRelatedWork W4310288564 @default.
- W1567643829 hasVolume "25" @default.
- W1567643829 isParatext "false" @default.
- W1567643829 isRetracted "false" @default.
- W1567643829 magId "1567643829" @default.
- W1567643829 workType "article" @default.