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• W1567649021 abstract "In this work we describe the presence of Fc-binding activity on the suckers and tegument of E. granulosus protoscoleces. A fraction (PSA-Fc+) from protoscolex somatic antigens was isolated by affinity chromatography on human Fc-gamma1-Sepharose. Analysis by SDS-PAGE of PSA-Fc+ showed that it contained two major components. Using mouse F(ab')2-human Fc chimaeric monoclonal antibodies we verified that PSA-Fc+ bound mainly to human Fc-gamma1 and Fc-gamma3 isotypes. In addition, one of the components of PSA-Fc+ showed proteolytic activity. Both, Fc-binding and proteolytic activities localized on the protoscolex surface, may play a relevant role in the host-parasite interaction." @default.
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• W1567649021 date "1998-09-01" @default.
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• W1567649021 title "Fc‐binding molecules specific for human IgG1 and IgG3 are present in<i>Echinococcus granulosus</i>protoscoleces" @default.
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• W1567649021 doi "https://doi.org/10.1046/j.1365-3024.1998.00147.x" @default.
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