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- W1567659690 abstract "Cryoglobulins may produce interference in results from electronic particle counters. Depending on their size, cold-precipitable globulin crystals can be counted as leucocytes and/or platelets. The Coulter Counter model S-Plus IV/D permits detection of this interference and its associated spurious counts by producing a characteristic WBC histogram accompanied by a leucocyte 'flag'. Using this instrument over a 1-year period, 10 cases of cryoglobulinaemia were detected, four from patients with lymphoproliferative disease and one from a patient with autoimmune disease. The remaining five were classified as essential mixed cryoglobulinaemia. The reproducibility of this instrument anomaly permits identification of the presence of cryoglobulins." @default.
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- W1567659690 date "1988-12-01" @default.
- W1567659690 modified "2023-09-23" @default.
- W1567659690 title "Detection of cryoglobulins by Coulter Counter model S-Plus IV/D" @default.
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- W1567659690 doi "https://doi.org/10.1111/j.1365-2257.1988.tb01194.x" @default.
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