FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W156766704> ?p ?o ?g. }

• W156766704 endingPage "302" @default.
• W156766704 startingPage "297" @default.
• W156766704 abstract "Objective An antiretroviral regimen based on lamivudine +stavudine+protease inhibitor impairs peripheral fat accrual in HIV-infected children and adolescents. We assess the effect on body composition parameters of replacing stavudine with tenofovir and protease inhibitor with efavirenz in paediatric patients. Methods A 96-week prospective study on 24 patients, (age range: 5.0–17.9 years) with stable undetectable HIV-1 loads, who were switched from stavudine to tenofovir and from protease inhibitor to efavirenz. Patient assessment included: body composition parameters measured by dual-energy X-ray absorptiometry (DXA), viral load and CD4 + T-count and percentage. As a control group for DXA data, we studied 143 healthy controls (HCs; age range: 4.9–20.0 years). Results Virological suppression and unchanged CD4 + T-cell count and percentage were maintained in all patients. At baseline, patients showed decreased total, arm and leg fat masses ( P<0.01) but a similar trunk fat mass to HCs. From baseline to week 96, patient fat mass increases were comparable to those for HCs (total fat: 1.3 vs 1.2 kg; fat in arms: 0.09 vs 0.08 kg; fat in legs: 0.5 vs 0.5 kg; trunk fat: 0.6 vs 0.6 kg). However, at week 96, total and leg fat mass in patients were still significantly lower than those in HCs ( P<0.02). At baseline and at week 96, lean mass in patients was similar to that expected in HCs. Conclusions Replacing stavudine with tenofovir and protease inhibitor with efavirenz for 96 weeks in lipoatrophic paediatrics patients led to a restoration of physiological fat accrual. Lipoatrophy did not progress but was still present, indicating the need for additional strategies." @default.
• W156766704 created "2016-06-24" @default.
• W156766704 creator A5016250106 @default.
• W156766704 creator A5027702804 @default.
• W156766704 creator A5064520148 @default.
• W156766704 creator A5074274894 @default.
• W156766704 creator A5075880036 @default.
• W156766704 creator A5085325102 @default.
• W156766704 creator A5085472795 @default.
• W156766704 creator A5090018866 @default.
• W156766704 date "2006-04-01" @default.
• W156766704 modified "2023-10-16" @default.
• W156766704 title "Normalization of Fat Accrual in Lipoatrophic, HIV-Infected Children Switched from Stavudine to Tenofovir and from Protease Inhibitor to Efavirenz" @default.
• W156766704 cites W1820999738 @default.
• W156766704 cites W1929260690 @default.
• W156766704 cites W1976022560 @default.
• W156766704 cites W1976890976 @default.
• W156766704 cites W2004027480 @default.
• W156766704 cites W2010178853 @default.
• W156766704 cites W2015113455 @default.
• W156766704 cites W2018435637 @default.
• W156766704 cites W2021144355 @default.
• W156766704 cites W2027386164 @default.
• W156766704 cites W2050999867 @default.
• W156766704 cites W2054385676 @default.
• W156766704 cites W2056578377 @default.
• W156766704 cites W2056779298 @default.
• W156766704 cites W2060796210 @default.
• W156766704 cites W2065116570 @default.
• W156766704 cites W2076812105 @default.
• W156766704 cites W2114888892 @default.
• W156766704 cites W2145565620 @default.
• W156766704 cites W2147449908 @default.
• W156766704 cites W2161209070 @default.
• W156766704 cites W2163955993 @default.
• W156766704 cites W2164529668 @default.
• W156766704 cites W2187888308 @default.
• W156766704 cites W2335165509 @default.
• W156766704 cites W2466441101 @default.
• W156766704 cites W2487039045 @default.
• W156766704 cites W4296927881 @default.
• W156766704 doi "https://doi.org/10.1177/135965350701200303" @default.
• W156766704 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17591019" @default.
• W156766704 hasPublicationYear "2006" @default.
• W156766704 type Work @default.
• W156766704 sameAs 156766704 @default.
• W156766704 citedByCount "26" @default.
• W156766704 countsByYear W1567667042012 @default.
• W156766704 countsByYear W1567667042013 @default.
• W156766704 countsByYear W1567667042014 @default.
• W156766704 countsByYear W1567667042015 @default.
• W156766704 countsByYear W1567667042018 @default.
• W156766704 countsByYear W1567667042020 @default.
• W156766704 crossrefType "journal-article" @default.
• W156766704 hasAuthorship W156766704A5016250106 @default.
• W156766704 hasAuthorship W156766704A5027702804 @default.
• W156766704 hasAuthorship W156766704A5064520148 @default.
• W156766704 hasAuthorship W156766704A5074274894 @default.
• W156766704 hasAuthorship W156766704A5075880036 @default.
• W156766704 hasAuthorship W156766704A5085325102 @default.
• W156766704 hasAuthorship W156766704A5085472795 @default.
• W156766704 hasAuthorship W156766704A5090018866 @default.
• W156766704 hasBestOaLocation W1567667041 @default.
• W156766704 hasConcept C120863210 @default.
• W156766704 hasConcept C126322002 @default.
• W156766704 hasConcept C142462285 @default.
• W156766704 hasConcept C147583825 @default.
• W156766704 hasConcept C159047783 @default.
• W156766704 hasConcept C2522874641 @default.
• W156766704 hasConcept C2777351918 @default.
• W156766704 hasConcept C2777869810 @default.
• W156766704 hasConcept C2779546735 @default.
• W156766704 hasConcept C2779889181 @default.
• W156766704 hasConcept C2780216070 @default.
• W156766704 hasConcept C2780593183 @default.
• W156766704 hasConcept C2780727368 @default.
• W156766704 hasConcept C2781432083 @default.
• W156766704 hasConcept C2993143319 @default.
• W156766704 hasConcept C3013748606 @default.
• W156766704 hasConcept C71924100 @default.
• W156766704 hasConcept C90924648 @default.
• W156766704 hasConceptScore W156766704C120863210 @default.
• W156766704 hasConceptScore W156766704C126322002 @default.
• W156766704 hasConceptScore W156766704C142462285 @default.
• W156766704 hasConceptScore W156766704C147583825 @default.
• W156766704 hasConceptScore W156766704C159047783 @default.
• W156766704 hasConceptScore W156766704C2522874641 @default.
• W156766704 hasConceptScore W156766704C2777351918 @default.
• W156766704 hasConceptScore W156766704C2777869810 @default.
• W156766704 hasConceptScore W156766704C2779546735 @default.
• W156766704 hasConceptScore W156766704C2779889181 @default.
• W156766704 hasConceptScore W156766704C2780216070 @default.
• W156766704 hasConceptScore W156766704C2780593183 @default.
• W156766704 hasConceptScore W156766704C2780727368 @default.
• W156766704 hasConceptScore W156766704C2781432083 @default.
• W156766704 hasConceptScore W156766704C2993143319 @default.
• W156766704 hasConceptScore W156766704C3013748606 @default.
• W156766704 hasConceptScore W156766704C71924100 @default.

• next