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- W1567732829 abstract "Summary The injection of purified gangliosides caused the production of specific antibodies in rabbits when administered with a carrier substance such as rabbit or sheep erythrocytes, Freund's adjuvant, whole human serum or bovine serum albumin. A separate antibody was also produced by the injection of erythrocytes coated with asialogangliosides. Anti-ganglioside and anti-asialoganglioside antibodies were demonstrated by hemagglutination, complement fixation and passive cutaneous anaphylaxis tests. Gangliosides exhibited blood group M and Rho(D) activity in hemagglutination inhibition tests and some, although weaker, blood group substance A and N activity. The intact ganglioside molecule was required for blood group activity. Asialogangliosides and crystalline N-acetylneuraminic acid were inactive in this regard." @default.
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- W1567732829 date "1963-03-01" @default.
- W1567732829 modified "2023-10-14" @default.
- W1567732829 title "Immunochemical Studies with Gangliosides" @default.
- W1567732829 doi "https://doi.org/10.4049/jimmunol.90.3.372" @default.
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