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- W1567794990 abstract "Background: The modified version of the Pulmonary Functional Status and Dyspnea Questionnaire (PFSDQ-M) is commonly used in COPD to obtain information about their symptoms and functional status. It has been shown to be responsive to change following pulmonary rehabilitation. The minimal important difference (MID) of the PFSDQ has never been established. Aim: To establish the MID of PFSDQ-M using different approaches. Methods: 416 patients with COPD (FEV1 42±15%pred) completed the PFSDQ-M before and after a 3-month pulmonary rehabilitation program (ΔCRDQ +16±12points, Δ6MWD +45±89m, both p≤0.001). The correlation between the ΔPFSDQ-M and the anchors ΔCRDQ and Δ6MWD was calculated. When r ≥ 0.3 linear regression analyses were performed to predict the MID from these anchors (i.e. establish the ΔPFSDQ corresponding with 10points ΔCRDQ, 2.5points ΔCRDQdys, 30m Δ6MWD). We also applied the distribution-based Cohen9s effect size technique to confirm the MID. Results: Anchor and distribution - based methods estimates are summarized in Table 1. Conclusion: The MID of the PFSDQ-M ranged from - 3 to -6 points in patients with moderate to very severe COPD. The estimate was similar with both statistical techniques. ER is a fellow of CAPES 1445/10-3" @default.
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- W1567794990 date "2011-09-01" @default.
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- W1567794990 title "The minimal important difference of the pulmonary functional status and dyspnea questionnaire – Modified version in patients with COPD" @default.
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