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- W1567821659 abstract "From 1979 to 1985, 67 children younger than 18 years with systemic lupus eryihematosus (SLE) had received renal biopsies. The diagnosis of SLE was made by using the recently revised criteria of the American Rheumatism Association. There were 9 boys and 58 girls. According to the morphologic classification of the World Health Organization (WHO), the initial renal biopsies were: Class I, 1 case (2%) ; Class Ⅱ, 14 cases (21%); Class Ⅲ, 19 cases (28%); Class Ⅳ 27 (40%); and Class Ⅴ, 6 cases (9%). Thirty-one cases received follow-up biopsy after an interval of six months to six years. The repeated biopsies showed that Jive needed renal pathologic reclassification: two had progressed from Class Ⅱ to Class Ⅳ; one, from Class Ⅲ to Class Ⅳ; and two reversed from Class Ⅳ to Class Ⅱ. Of the patients with Class Ⅱ nephritis at the initial biopsy, four (29%) had changed to chronic renal failure (CRF); with Class Ⅲ nephritis, one (5%) had CRF; with Class Ⅳ nephritis, 8 (30%) had CRF and with Class Ⅴ nephritis, 4 (67%) had progressed to CRF. Renal lesions correlated with clinical and laboratory manifestations at the time of renal biopsy; however, they are no, good indicators for long-term predictions of outcome because of the possibility of change in pathologic patterns from either natural course and/or through treatment. Aggressive treatment may help reverse severe pathologic lesions associated with clinical and laboratory improvement." @default.
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- W1567821659 date "1987-04-01" @default.
- W1567821659 modified "2023-09-23" @default.
- W1567821659 title "Renal Biopsy Findings on Childhood Systemic Lupus Erythematosus" @default.
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