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• W1567849932 abstract "Abstract Aflatoxins are the secondary toxic metabolites produced by a group of toxigenic fungi. They are the common contaminants of food and feed that cause severe economic and health losses. The present study concerns control of aflatoxin B 1 ( AFB 1 ) synthesis from A spergillus flavus , direct degradation of AFB 1 and its decontamination on rice by the aqueous extract of O cimum tenuiflorum . In the presence of O cimum extract, the culture of A . flavus in yeast extract sucrose medium showed an increase in mycelium mass and reduction in AFB 1 production up to 64%. The direct treatment of AFB 1 with extract at 85 C for 4 h led to 74.7% degradation. Whereas in rice spiked with AFB 1 , the degradation was 70.2%. This degradation resulted in detoxification, which was confirmed using mammalian cell culture method. The results of the study showed that O cimum extract can be used efficiently to eliminate the AFB 1 threat. Practical Applications Mycotoxin contamination of food and feed is a major concern in food and agricultural sector. Continuous research in the area of physical and chemical methods to eliminate mycotoxin is being carried out but there is a need to find more safe natural agents to reduce the mycotoxin threat. This study demonstrates the efficacy of O cimum as a safe additive, which not only inhibits the aflatoxin production but also degrades the existing toxin. Hence, the O cimum can be safely used for the reduction and removal of aflatoxin to the safe level from the food and feed chain." @default.
• W1567849932 created "2016-06-24" @default.
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• W1567849932 date "2013-05-26" @default.
• W1567849932 modified "2023-10-03" @default.
• W1567849932 title "Aflatoxin Detoxification Potential of <i>Ocimum Tenuiflorum</i>" @default.
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• W1567849932 doi "https://doi.org/10.1111/jfs.12048" @default.
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