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- W1567886487 abstract "Much like an individual's hairstyle, hair fibers along the scalp see a number of changes over the course of one's lifetime. As the decades pass, the shine and volume synonymous with youthful hair may give way to thin, dull, and brittle hair commonly associated with aging. These changes are a result of a compilation of genetic and environmental elements influencing the cells of the hair follicle, specifically the hair follicle stem cells and melanocytes. Telomere shortening, decrease in cell numbers, and particular transcription factors have all been implicated in this process. In turn, these molecular alterations lead to structural modifications of the hair fiber, decrease in melanin production, and lengthening of the telogen phase of the hair cycle. Despite this inevitable progression with aging, there exists an array of treatments such as light therapy, minoxidil, and finasteride which have been designed to mitigate the effects of aging, particularly balding and thinning hair. Although each works through a different mechanism, all aim to maintain or potentially restore the youthful quality of hair." @default.
- W1567886487 created "2016-06-24" @default.
- W1567886487 creator A5019296139 @default.
- W1567886487 creator A5051100756 @default.
- W1567886487 date "2015-01-01" @default.
- W1567886487 modified "2023-09-29" @default.
- W1567886487 title "Normal and Aging Hair Biology and Structure ‘Aging and Hair'" @default.
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- W1567886487 doi "https://doi.org/10.1159/000369594" @default.
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