FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1567895511> ?p ?o ?g. }

• W1567895511 endingPage "364" @default.
• W1567895511 startingPage "354" @default.
• W1567895511 abstract "Object The intracranial pulse pressure is often increased when neuropathology is present, particularly in cases of increased intracranial pressure (ICP) such as occurs in hydrocephalus. This pulse pressure is assumed to originate from arterial blood pressure oscillations entering the cranium; the fact that there is a coupling between the arterial blood pressure and the ICP is undisputed. In this study, the nature of this coupling and how it changes under conditions of increased ICP are investigated. Methods In 12 normal dogs, intracarotid and parenchymal pulse pressure were measured and their coupling was characterized using amplitude and phase transfer function analysis. Mean intracranial ICP was manipulated via infusions of isotonic saline into the spinal subarachnoid space, and changes in transfer function were monitored. Results Under normal conditions, the ICP wave led the arterial wave, and there was a minimum in the pulse pressure amplitude near the frequency of the heart rate. Under conditions of decreased intracranial compliance, the ICP wave began to lag behind the arterial wave and increased significantly in amplitude. Most interestingly, in many animals the pulse pressure exhibited a minimum in amplitude at a mean pressure that coincided with the transition from a leading to lagging ICP wave. Conclusions This transfer function behavior is characteristic of a resonant notch system. This may represent a component of the intracranial Windkessel mechanism, which protects the microvasculature from arterial pulsatility. The impairment of this resonant notch system may play a role in the altered pulse pressure in conditions such as hydrocephalus and traumatic brain swelling. New models of intracranial dynamics are needed for understanding the frequency-sensitive behavior elucidated in these studies and could open a path for development of new therapies that are geared toward addressing the pulsation dysfunction in pathological conditions, such as hydrocephalus and traumatic brain injury, affecting ICP and flow dynamics." @default.
• W1567895511 created "2016-06-24" @default.
• W1567895511 creator A5008444122 @default.
• W1567895511 creator A5020688139 @default.
• W1567895511 creator A5024429193 @default.
• W1567895511 creator A5035394411 @default.
• W1567895511 creator A5055640462 @default.
• W1567895511 creator A5059560314 @default.
• W1567895511 date "2009-05-01" @default.
• W1567895511 modified "2023-10-14" @default.
• W1567895511 title "Resonant and notch behavior in intracranial pressure dynamics" @default.
• W1567895511 cites W1549826571 @default.
• W1567895511 cites W1563303467 @default.
• W1567895511 cites W1769158751 @default.
• W1567895511 cites W1965315954 @default.
• W1567895511 cites W1979317731 @default.
• W1567895511 cites W1982175050 @default.
• W1567895511 cites W1983778750 @default.
• W1567895511 cites W1984325502 @default.
• W1567895511 cites W1988963161 @default.
• W1567895511 cites W1989051104 @default.
• W1567895511 cites W1994661976 @default.
• W1567895511 cites W2000680498 @default.
• W1567895511 cites W2015728745 @default.
• W1567895511 cites W2023718374 @default.
• W1567895511 cites W2034073751 @default.
• W1567895511 cites W2037528123 @default.
• W1567895511 cites W2037950209 @default.
• W1567895511 cites W2039954795 @default.
• W1567895511 cites W2041416860 @default.
• W1567895511 cites W2042473820 @default.
• W1567895511 cites W2043511110 @default.
• W1567895511 cites W2047044360 @default.
• W1567895511 cites W2047463556 @default.
• W1567895511 cites W2059044176 @default.
• W1567895511 cites W2059712928 @default.
• W1567895511 cites W2061102313 @default.
• W1567895511 cites W2062841580 @default.
• W1567895511 cites W2067996069 @default.
• W1567895511 cites W2071876346 @default.
• W1567895511 cites W2072137725 @default.
• W1567895511 cites W2074135923 @default.
• W1567895511 cites W2075068256 @default.
• W1567895511 cites W2077049663 @default.
• W1567895511 cites W2078984973 @default.
• W1567895511 cites W2082340817 @default.
• W1567895511 cites W2083655998 @default.
• W1567895511 cites W2087849239 @default.
• W1567895511 cites W2090501027 @default.
• W1567895511 cites W2099453882 @default.
• W1567895511 cites W2117535864 @default.
• W1567895511 cites W2120692956 @default.
• W1567895511 cites W2138970529 @default.
• W1567895511 cites W2139314414 @default.
• W1567895511 cites W2142656502 @default.
• W1567895511 cites W2144855997 @default.
• W1567895511 cites W2150521986 @default.
• W1567895511 cites W2168349790 @default.
• W1567895511 cites W2171051145 @default.
• W1567895511 cites W4293370187 @default.
• W1567895511 doi "https://doi.org/10.3171/2009.1.peds08109" @default.
• W1567895511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19409013" @default.
• W1567895511 hasPublicationYear "2009" @default.
• W1567895511 type Work @default.
• W1567895511 sameAs 1567895511 @default.
• W1567895511 citedByCount "26" @default.
• W1567895511 countsByYear W15678955112012 @default.
• W1567895511 countsByYear W15678955112013 @default.
• W1567895511 countsByYear W15678955112014 @default.
• W1567895511 countsByYear W15678955112015 @default.
• W1567895511 countsByYear W15678955112016 @default.
• W1567895511 countsByYear W15678955112017 @default.
• W1567895511 countsByYear W15678955112018 @default.
• W1567895511 countsByYear W15678955112019 @default.
• W1567895511 countsByYear W15678955112021 @default.
• W1567895511 countsByYear W15678955112022 @default.
• W1567895511 countsByYear W15678955112023 @default.
• W1567895511 crossrefType "journal-article" @default.
• W1567895511 hasAuthorship W1567895511A5008444122 @default.
• W1567895511 hasAuthorship W1567895511A5020688139 @default.
• W1567895511 hasAuthorship W1567895511A5024429193 @default.
• W1567895511 hasAuthorship W1567895511A5035394411 @default.
• W1567895511 hasAuthorship W1567895511A5055640462 @default.
• W1567895511 hasAuthorship W1567895511A5059560314 @default.
• W1567895511 hasConcept C120665830 @default.
• W1567895511 hasConcept C121332964 @default.
• W1567895511 hasConcept C126322002 @default.
• W1567895511 hasConcept C141071460 @default.
• W1567895511 hasConcept C164705383 @default.
• W1567895511 hasConcept C17140001 @default.
• W1567895511 hasConcept C2778134817 @default.
• W1567895511 hasConcept C2779651940 @default.
• W1567895511 hasConcept C2780167933 @default.
• W1567895511 hasConcept C2780813603 @default.
• W1567895511 hasConcept C2780954326 @default.
• W1567895511 hasConcept C42219234 @default.
• W1567895511 hasConcept C46141821 @default.
• W1567895511 hasConcept C71924100 @default.

• next