Matches in SemOpenAlex for { <https://semopenalex.org/work/W156791144> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W156791144 endingPage "92" @default.
- W156791144 startingPage "83" @default.
- W156791144 abstract "Calcium concentration in gastric juice is lower then other electrolytes. The mechanism of its transport remained unknown. The aim of the study was to evaluate influence of pentagastrin on calcium concentration in gastric juice in humans. Ten patients were examined (4 females and 6 males, mean age 46.8 range 33-67), four with duodenal ulcer, three with achalasia cardiae and three with Addison-Biermer anemia. Pentagastrin--PG (Cambridge Laboratories, Newcastle, United Kingdom) was injected subcutaneously after overnight fast in dose of 6 micrograms/kg of body weight. Nosogastric tube was located in body of the stomach near large curvature and connected to suction of--40 mmHg pressure. Gastric juice was collected during subsequent five 15 minutes periods (first fasted and four periods after stimulation with PG). Calcium concentration was measured in each sample by fluorescentic titration method with EGTA. Statistic analysis was performed with student t test. Mean fasted and stimulated calcium concentrations were 0.83; 0.44; 0.54; 0.37 and 0.95 mmol/l respectively. Ca2+ concentration range in fasted state from 0.21 to 1.75 mmol/l and from 0.07 to 0.27 mmol/l by maximal stimulation. Calcium concentration decreased immediately after stimulation (significance p = 0.0025). This strong effect persisted throughout the period of stimulation. Calcium output was 0.064; 0.029; 0.032; 0.018 and 0.17 mmol/15 min respectively. Two phases of decrease of the calcium output were observed: first, fast decrease immediately after pentagastrin injection and second, slower, between 30 and 45 minute after stimulation (p < 0.01 and 0.02 respectively). Calcium concentration in gastric juice decreases after stimulation with pentagastin (p = 0.0025). Calcium concentration was lower in Addison-Biermer anemia and higher in duodenal ulcer patients then in healthy control. We conclude that calcium ions are not actively secreted by gastric mucosa. Their presence in gastric juice is a result of leak from mucosal cells and remains opposite to their metabolic activity." @default.
- W156791144 created "2016-06-24" @default.
- W156791144 creator A5027207456 @default.
- W156791144 creator A5051978715 @default.
- W156791144 creator A5059049938 @default.
- W156791144 creator A5080171147 @default.
- W156791144 date "1999-01-01" @default.
- W156791144 modified "2023-09-25" @default.
- W156791144 title "[The effect of pentagastrin on calcium ion concentration in gastric juice]." @default.
- W156791144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10909477" @default.
- W156791144 hasPublicationYear "1999" @default.
- W156791144 type Work @default.
- W156791144 sameAs 156791144 @default.
- W156791144 citedByCount "0" @default.
- W156791144 crossrefType "journal-article" @default.
- W156791144 hasAuthorship W156791144A5027207456 @default.
- W156791144 hasAuthorship W156791144A5051978715 @default.
- W156791144 hasAuthorship W156791144A5059049938 @default.
- W156791144 hasAuthorship W156791144A5080171147 @default.
- W156791144 hasConcept C126322002 @default.
- W156791144 hasConcept C134018914 @default.
- W156791144 hasConcept C176685330 @default.
- W156791144 hasConcept C185592680 @default.
- W156791144 hasConcept C24998067 @default.
- W156791144 hasConcept C2777504413 @default.
- W156791144 hasConcept C2778758028 @default.
- W156791144 hasConcept C2779377912 @default.
- W156791144 hasConcept C2779422922 @default.
- W156791144 hasConcept C519063684 @default.
- W156791144 hasConcept C71924100 @default.
- W156791144 hasConceptScore W156791144C126322002 @default.
- W156791144 hasConceptScore W156791144C134018914 @default.
- W156791144 hasConceptScore W156791144C176685330 @default.
- W156791144 hasConceptScore W156791144C185592680 @default.
- W156791144 hasConceptScore W156791144C24998067 @default.
- W156791144 hasConceptScore W156791144C2777504413 @default.
- W156791144 hasConceptScore W156791144C2778758028 @default.
- W156791144 hasConceptScore W156791144C2779377912 @default.
- W156791144 hasConceptScore W156791144C2779422922 @default.
- W156791144 hasConceptScore W156791144C519063684 @default.
- W156791144 hasConceptScore W156791144C71924100 @default.
- W156791144 hasIssue "3-4" @default.
- W156791144 hasLocation W1567911441 @default.
- W156791144 hasOpenAccess W156791144 @default.
- W156791144 hasPrimaryLocation W1567911441 @default.
- W156791144 hasRelatedWork W1963590959 @default.
- W156791144 hasRelatedWork W1973606441 @default.
- W156791144 hasRelatedWork W1992021277 @default.
- W156791144 hasRelatedWork W1999581759 @default.
- W156791144 hasRelatedWork W2023352231 @default.
- W156791144 hasRelatedWork W2027476501 @default.
- W156791144 hasRelatedWork W2056454041 @default.
- W156791144 hasRelatedWork W2064416809 @default.
- W156791144 hasRelatedWork W2136418839 @default.
- W156791144 hasRelatedWork W2154922992 @default.
- W156791144 hasVolume "40" @default.
- W156791144 isParatext "false" @default.
- W156791144 isRetracted "false" @default.
- W156791144 magId "156791144" @default.
- W156791144 workType "article" @default.