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• W1567953868 abstract "Sleep-disordered breathing (SDB) includes a range of conditions characterized by abnormalities in the frequency and/or depth of breathing during sleep. Cessations in breathing rhythm (apneas) are momentary and often cyclical, while reductions in breath amplitude (hypopneas) may be momentary or sustained (Dempsey et al., 2010). Obstructive sleep apnea (OSA)/hypopnea syndrome (HS), obesity hypoventilation syndrome, central sleep apnea (CSA), upper airway resistance syndrome, and Cheyne-Stokes respiration (CSR) are the primary sleep-related respiratory disorders. Although CSA is accompanied by alterations in neural input, the obstruction characteristic of OSA, the most common form of SDB, is also neurally mediated (Veasey, 2009). Intermittent episodes of partial or complete obstruction of the upper airway during sleep characteristic of OSA result from collapse of the upper airway. The concomitant disruption of normal ventilation and sleep architecture is typically associated with snoring, repeated arousals from sleep, and daytime sleepiness (Bradley & Floras, 2003; Lattimore et al, 2003; Quan & Gersh, 2004; Shamsuzzaman et al; 2003;). Prevalence studies indicate that SDB, and particularly OSA, are common problems worldwide, affecting millions of individuals. However, OSA is also considered to be largely undiagnosed (Young et al, 1993; Young et al, 2002; Lavie, 2007). In the United States, for example, the estimated proportions of adults with OSA who are not diagnosed range from 60% to 80%, with an even greater under diagnosis suspected for children (Carter III, 2008). The increasing prevalence can be intuitively associated with the global obesity epidemic; however, a reverse association has also been postulated based on emerging evidence that OSA promotes weight gain (Carter III, 2008). The clinical relevance of OSA was thought for years to be limited to what was considered a benign but often annoying manifestation as snoring, ranging to the possibly serious consequences of daytime sleepiness affecting cognitive function and work performance, mental state, and driving ability. OSA is now known to be a risk factor for other serious conditions, and has been associated with increased cardiovascular morbidity and mortality (Bradley & Floras, 2009; Devulapally et al., 2009; Lattimore et al, 2003; Lopez-Jiminez et al., 2008). Cardiac arrhythmias are common in OSA, and the potential link between tachyarrhythmias and bradyarrhythmias and adverse outcomes in OSA patients continues to be an important area of research (Chan & Wilcox, 2010; Verrier & Josephson, 2009). However, the complex cascade of events triggered by OSA, the difficulty in determining" @default.
• W1567953868 created "2016-06-24" @default.
• W1567953868 creator A5072341911 @default.
• W1567953868 date "2012-02-29" @default.
• W1567953868 modified "2023-10-16" @default.
• W1567953868 title "Sleep-Related Breathing Disorders and Cardiac Arrhythmia" @default.
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• W1567953868 doi "https://doi.org/10.5772/31661" @default.
• W1567953868 hasPublicationYear "2012" @default.
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