Matches in SemOpenAlex for { <https://semopenalex.org/work/W156798452> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W156798452 endingPage "3" @default.
- W156798452 startingPage "321" @default.
- W156798452 abstract "A 47-year-old woman with myasthenia gravis for last 11 years was admitted because of relapsed muscle weakness, hypermenorrhea and thrombocytopenia. Physical and neurological examinations revealed diplopia, proximal muscle weakness and purpuras on the left arm and bilateral legs. Repeated hematological examinations revealed cyclic fluctuation of platelet counts which spontaneously changed from the nadir levels of 12-27 x 10(3)/microliters to the peak levels of 150-400 x 10(3)/microliters. The platelet count reached a nadir at the onset of menstruation. Platelet-associated IgG (PAIgG) was within normal level when platelet count was at an increasing phase. Survival time of autologous platelets was normal when platelet count was at an increasing phase. Megakaryocytes in the bone marrow were apparently normal at the nadir phase. The patient's serum obtained at the nadir of platelet count significantly suppressed megakaryocyte colony forming unit (Meg-CFU) formation in comparison with that after the stabilization of platelet count, suggesting that this cyclic thrombocytopenia was secondary to cyclic hypoproduction of megakaryocytes caused by a suppressive factor. On the other hand muscle weakness showed no cyclic fluctuation. Administration of 60 mg/day prednisolone stabilized the platelet count at about 280 x 10(3)/microliters, abolished hypermenorrhea and gradually improved muscle weakness. These findings suggested autoimmune mechanism in the production of a Meg-CFU-suppressive factor might be involved in the pathogenesis of thrombocytopenia." @default.
- W156798452 created "2016-06-24" @default.
- W156798452 creator A5009149908 @default.
- W156798452 creator A5030459937 @default.
- W156798452 creator A5031655325 @default.
- W156798452 creator A5065661878 @default.
- W156798452 creator A5070611644 @default.
- W156798452 creator A5076626565 @default.
- W156798452 date "1992-03-01" @default.
- W156798452 modified "2023-09-25" @default.
- W156798452 title "[A case of myasthenia gravis complicated by cyclic thrombocytopenia]." @default.
- W156798452 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1628457" @default.
- W156798452 hasPublicationYear "1992" @default.
- W156798452 type Work @default.
- W156798452 sameAs 156798452 @default.
- W156798452 citedByCount "0" @default.
- W156798452 crossrefType "journal-article" @default.
- W156798452 hasAuthorship W156798452A5009149908 @default.
- W156798452 hasAuthorship W156798452A5030459937 @default.
- W156798452 hasAuthorship W156798452A5031655325 @default.
- W156798452 hasAuthorship W156798452A5065661878 @default.
- W156798452 hasAuthorship W156798452A5070611644 @default.
- W156798452 hasAuthorship W156798452A5076626565 @default.
- W156798452 hasConcept C109159458 @default.
- W156798452 hasConcept C126322002 @default.
- W156798452 hasConcept C134018914 @default.
- W156798452 hasConcept C141071460 @default.
- W156798452 hasConcept C2775934546 @default.
- W156798452 hasConcept C2776418732 @default.
- W156798452 hasConcept C2778105408 @default.
- W156798452 hasConcept C2779705218 @default.
- W156798452 hasConcept C2779999465 @default.
- W156798452 hasConcept C2780247198 @default.
- W156798452 hasConcept C28328180 @default.
- W156798452 hasConcept C2909745897 @default.
- W156798452 hasConcept C54355233 @default.
- W156798452 hasConcept C71924100 @default.
- W156798452 hasConcept C86803240 @default.
- W156798452 hasConcept C89560881 @default.
- W156798452 hasConcept C90924648 @default.
- W156798452 hasConceptScore W156798452C109159458 @default.
- W156798452 hasConceptScore W156798452C126322002 @default.
- W156798452 hasConceptScore W156798452C134018914 @default.
- W156798452 hasConceptScore W156798452C141071460 @default.
- W156798452 hasConceptScore W156798452C2775934546 @default.
- W156798452 hasConceptScore W156798452C2776418732 @default.
- W156798452 hasConceptScore W156798452C2778105408 @default.
- W156798452 hasConceptScore W156798452C2779705218 @default.
- W156798452 hasConceptScore W156798452C2779999465 @default.
- W156798452 hasConceptScore W156798452C2780247198 @default.
- W156798452 hasConceptScore W156798452C28328180 @default.
- W156798452 hasConceptScore W156798452C2909745897 @default.
- W156798452 hasConceptScore W156798452C54355233 @default.
- W156798452 hasConceptScore W156798452C71924100 @default.
- W156798452 hasConceptScore W156798452C86803240 @default.
- W156798452 hasConceptScore W156798452C89560881 @default.
- W156798452 hasConceptScore W156798452C90924648 @default.
- W156798452 hasIssue "3" @default.
- W156798452 hasLocation W1567984521 @default.
- W156798452 hasOpenAccess W156798452 @default.
- W156798452 hasPrimaryLocation W1567984521 @default.
- W156798452 hasRelatedWork W1990306022 @default.
- W156798452 hasRelatedWork W2060611519 @default.
- W156798452 hasRelatedWork W2097813958 @default.
- W156798452 hasRelatedWork W2154803724 @default.
- W156798452 hasRelatedWork W2410053642 @default.
- W156798452 hasRelatedWork W2413330470 @default.
- W156798452 hasRelatedWork W2605607543 @default.
- W156798452 hasRelatedWork W2900764113 @default.
- W156798452 hasRelatedWork W3124709147 @default.
- W156798452 hasRelatedWork W3202048764 @default.
- W156798452 hasVolume "32" @default.
- W156798452 isParatext "false" @default.
- W156798452 isRetracted "false" @default.
- W156798452 magId "156798452" @default.
- W156798452 workType "article" @default.