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• W1567993829 abstract "Summary Seventy‐two patients undergoing routine surgical procedures under propofol‐remifentanil anaesthesia were randomly assigned to receive either standard clinical practice ( n = 35) or standard practice plus monitoring of depth of anaesthesia with M‐Entropy ( n = 37). Patients in the standard practice group received more propofol than the entropy group (mean (SD) 95 (14) vs 81 (22) μg.kg −1 .min −1 , respectively; p < 0.01), and less remifentanil (0.39 (0.08) vs 0.46 (0.08) μg.kg −1 .min −1 , respectively; p < 0.001). Loss of consciousness was best predicted by BIS (prediction probability (P K ) 0.96) and response entropy (P K 0.93), whereas emergence was best predicted by response entropy (P K 0.94). The frequency of unwanted patient responses was higher in the standard practice group than in the entropy group (47 vs 27 total events, respectively; p < 0.01). Both regimens resulted in fast recovery with no clinical advantage for either one. There were no significant differences in haemodynamic parameters, postoperative nausea and vomiting or satisfaction with the procedure." @default.
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• W1567993829 date "2007-11-05" @default.
• W1567993829 modified "2023-10-18" @default.
• W1567993829 title "M-Entropy guidance vs standard practice during propofol-remifentanil anaesthesia: a randomised controlled trial*" @default.
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• W1567993829 doi "https://doi.org/10.1111/j.1365-2044.2007.05252.x" @default.
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