Matches in SemOpenAlex for { <https://semopenalex.org/work/W1568106488> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W1568106488 endingPage "500" @default.
- W1568106488 startingPage "492" @default.
- W1568106488 abstract "Disaccharidase (lactase, maltase, sucrase, and palatinase) assays were performed on small intestinal mucosal biopsies obtained from 28 patients with cystic fibrosis and 90 controls. Seven patients with cystic fibrosis showed a significant reduction in lactase activity with normal values for sucrase, maltase, and palatinase. In the remaining 21 patients the enzymatic activities, expressed in units per gram of wet weight of tissue and per gram of protein, were comparable with the 90 controls. The mucosal histology showed normal villous structure. Oral tolerance tests for glucose revealed excellent absorption in all cases tested. Patients with cystic fibrosis having normal lactase activity also had good lactose absorption. However, in the patients with lactase deficiency, flat oral lactose tolerance tests were found. Five of the seven patients with lactase deficiency were able to tolerate some lactose, whereas two others were very intolerant and required elimination of lactose from their diet. This study brings out the high incidence of intestinal lactase deficiency in patients with cystic fibrosis and suggests that the lactase deficiency may be a primary genetic disorder. At present no explanation for this genetic association is available." @default.
- W1568106488 created "2016-06-24" @default.
- W1568106488 creator A5043019346 @default.
- W1568106488 creator A5049986672 @default.
- W1568106488 creator A5053527539 @default.
- W1568106488 creator A5090323372 @default.
- W1568106488 date "1968-09-01" @default.
- W1568106488 modified "2023-10-05" @default.
- W1568106488 title "LACTASE DEFICIENCY IN PATIENTS WITH CYSTIC FIBROSIS" @default.
- W1568106488 doi "https://doi.org/10.1542/peds.42.3.492" @default.
- W1568106488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5677488" @default.
- W1568106488 hasPublicationYear "1968" @default.
- W1568106488 type Work @default.
- W1568106488 sameAs 1568106488 @default.
- W1568106488 citedByCount "32" @default.
- W1568106488 countsByYear W15681064882014 @default.
- W1568106488 countsByYear W15681064882021 @default.
- W1568106488 crossrefType "journal-article" @default.
- W1568106488 hasAuthorship W1568106488A5043019346 @default.
- W1568106488 hasAuthorship W1568106488A5049986672 @default.
- W1568106488 hasAuthorship W1568106488A5053527539 @default.
- W1568106488 hasAuthorship W1568106488A5090323372 @default.
- W1568106488 hasConcept C126322002 @default.
- W1568106488 hasConcept C134018914 @default.
- W1568106488 hasConcept C146201443 @default.
- W1568106488 hasConcept C181199279 @default.
- W1568106488 hasConcept C2776039999 @default.
- W1568106488 hasConcept C2776938444 @default.
- W1568106488 hasConcept C2777432071 @default.
- W1568106488 hasConcept C2777882243 @default.
- W1568106488 hasConcept C2778649499 @default.
- W1568106488 hasConcept C2778724459 @default.
- W1568106488 hasConcept C2778974006 @default.
- W1568106488 hasConcept C2780439177 @default.
- W1568106488 hasConcept C55493867 @default.
- W1568106488 hasConcept C71924100 @default.
- W1568106488 hasConcept C86803240 @default.
- W1568106488 hasConcept C90924648 @default.
- W1568106488 hasConceptScore W1568106488C126322002 @default.
- W1568106488 hasConceptScore W1568106488C134018914 @default.
- W1568106488 hasConceptScore W1568106488C146201443 @default.
- W1568106488 hasConceptScore W1568106488C181199279 @default.
- W1568106488 hasConceptScore W1568106488C2776039999 @default.
- W1568106488 hasConceptScore W1568106488C2776938444 @default.
- W1568106488 hasConceptScore W1568106488C2777432071 @default.
- W1568106488 hasConceptScore W1568106488C2777882243 @default.
- W1568106488 hasConceptScore W1568106488C2778649499 @default.
- W1568106488 hasConceptScore W1568106488C2778724459 @default.
- W1568106488 hasConceptScore W1568106488C2778974006 @default.
- W1568106488 hasConceptScore W1568106488C2780439177 @default.
- W1568106488 hasConceptScore W1568106488C55493867 @default.
- W1568106488 hasConceptScore W1568106488C71924100 @default.
- W1568106488 hasConceptScore W1568106488C86803240 @default.
- W1568106488 hasConceptScore W1568106488C90924648 @default.
- W1568106488 hasIssue "3" @default.
- W1568106488 hasLocation W15681064881 @default.
- W1568106488 hasLocation W15681064882 @default.
- W1568106488 hasOpenAccess W1568106488 @default.
- W1568106488 hasPrimaryLocation W15681064881 @default.
- W1568106488 hasRelatedWork W1568106488 @default.
- W1568106488 hasRelatedWork W1578090061 @default.
- W1568106488 hasRelatedWork W1600876057 @default.
- W1568106488 hasRelatedWork W1881309253 @default.
- W1568106488 hasRelatedWork W1980506650 @default.
- W1568106488 hasRelatedWork W1988760866 @default.
- W1568106488 hasRelatedWork W2052973036 @default.
- W1568106488 hasRelatedWork W2094428929 @default.
- W1568106488 hasRelatedWork W2154972461 @default.
- W1568106488 hasRelatedWork W4205788449 @default.
- W1568106488 hasVolume "42" @default.
- W1568106488 isParatext "false" @default.
- W1568106488 isRetracted "false" @default.
- W1568106488 magId "1568106488" @default.
- W1568106488 workType "article" @default.