FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1568573049> ?p ?o ?g. }

• W1568573049 endingPage "2345" @default.
• W1568573049 startingPage "2338" @default.
• W1568573049 abstract "Abstract The regulation of CCR6 (chemokine receptor 6) expression during B-cell ontogeny and antigen-driven B-cell differentiation was analyzed. None of the CD34+Lin− hematopoietic stem cell progenitors or the CD34+CD19+ (pro-B) or the CD19+CD10+ (pre-B/immature B cells) B-cell progenitors expressed CCR6. CCR6 is acquired when CD10 is lost and B-cell progeny matures, entering into the surface immunoglobulin D+ (sIgD+) mature B-cell pool. CCR6 is expressed by all bone marrow–, umbilical cord blood–, and peripheral blood–derived naive and/or memory B cells but is absent from germinal center (GC) B cells of secondary lymphoid organs. CCR6 is down-regulated after B-cell antigen receptor triggering and remains absent during differentiation into immunoglobulin-secreting plasma cells, whereas it is reacquired at the stage of post-GC memory B cells. Thus, within the B-cell compartment, CCR6 expression is restricted to functionally mature cells capable of responding to antigen challenge. In transmigration chemotactic assays, macrophage inflammatory protein (MIP)-3α/CC chemokine ligand 20 (CCL20) induced vigorous migration of B cells with differential chemotactic preference toward sIgD− memory B cells. These data suggest that restricted patterns of CCR6 expression and MIP-3α/CCL20 responsiveness are integral parts of the process of B-lineage maturation and antigen-driven B-cell differentiation." @default.
• W1568573049 created "2016-06-24" @default.
• W1568573049 creator A5024775766 @default.
• W1568573049 creator A5031099399 @default.
• W1568573049 creator A5040786229 @default.
• W1568573049 creator A5043923221 @default.
• W1568573049 creator A5072226202 @default.
• W1568573049 creator A5077897116 @default.
• W1568573049 creator A5079208984 @default.
• W1568573049 date "2000-10-01" @default.
• W1568573049 modified "2023-09-30" @default.
• W1568573049 title "Regulation of CCR6 chemokine receptor expression and responsiveness to macrophage inflammatory protein-3α/CCL20 in human B cells" @default.
• W1568573049 cites W1625203433 @default.
• W1568573049 cites W1972496142 @default.
• W1568573049 cites W1981480494 @default.
• W1568573049 cites W1982854219 @default.
• W1568573049 cites W2016397844 @default.
• W1568573049 cites W2026549568 @default.
• W1568573049 cites W2039409588 @default.
• W1568573049 cites W2044063819 @default.
• W1568573049 cites W2048646012 @default.
• W1568573049 cites W2059413226 @default.
• W1568573049 cites W2081769332 @default.
• W1568573049 cites W2087976424 @default.
• W1568573049 cites W209718637 @default.
• W1568573049 cites W2098509726 @default.
• W1568573049 cites W2103384599 @default.
• W1568573049 cites W2103555767 @default.
• W1568573049 cites W2104159258 @default.
• W1568573049 cites W2114123652 @default.
• W1568573049 cites W2118515142 @default.
• W1568573049 cites W2132182183 @default.
• W1568573049 cites W2138769023 @default.
• W1568573049 cites W2157069655 @default.
• W1568573049 cites W2160272188 @default.
• W1568573049 cites W2171429483 @default.
• W1568573049 cites W2403058886 @default.
• W1568573049 cites W4211264883 @default.
• W1568573049 cites W4296792904 @default.
• W1568573049 doi "https://doi.org/10.1182/blood.v96.7.2338" @default.
• W1568573049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11001880" @default.
• W1568573049 hasPublicationYear "2000" @default.
• W1568573049 type Work @default.
• W1568573049 sameAs 1568573049 @default.
• W1568573049 citedByCount "158" @default.
• W1568573049 countsByYear W15685730492012 @default.
• W1568573049 countsByYear W15685730492013 @default.
• W1568573049 countsByYear W15685730492014 @default.
• W1568573049 countsByYear W15685730492015 @default.
• W1568573049 countsByYear W15685730492016 @default.
• W1568573049 countsByYear W15685730492017 @default.
• W1568573049 countsByYear W15685730492018 @default.
• W1568573049 countsByYear W15685730492019 @default.
• W1568573049 countsByYear W15685730492020 @default.
• W1568573049 countsByYear W15685730492021 @default.
• W1568573049 countsByYear W15685730492022 @default.
• W1568573049 countsByYear W15685730492023 @default.
• W1568573049 crossrefType "journal-article" @default.
• W1568573049 hasAuthorship W1568573049A5024775766 @default.
• W1568573049 hasAuthorship W1568573049A5031099399 @default.
• W1568573049 hasAuthorship W1568573049A5040786229 @default.
• W1568573049 hasAuthorship W1568573049A5043923221 @default.
• W1568573049 hasAuthorship W1568573049A5072226202 @default.
• W1568573049 hasAuthorship W1568573049A5077897116 @default.
• W1568573049 hasAuthorship W1568573049A5079208984 @default.
• W1568573049 hasConcept C12823836 @default.
• W1568573049 hasConcept C13373296 @default.
• W1568573049 hasConcept C147483822 @default.
• W1568573049 hasConcept C159654299 @default.
• W1568573049 hasConcept C200180986 @default.
• W1568573049 hasConcept C203014093 @default.
• W1568573049 hasConcept C2776090121 @default.
• W1568573049 hasConcept C2776914184 @default.
• W1568573049 hasConcept C2778453870 @default.
• W1568573049 hasConcept C2778957590 @default.
• W1568573049 hasConcept C67662055 @default.
• W1568573049 hasConcept C83360876 @default.
• W1568573049 hasConcept C86803240 @default.
• W1568573049 hasConcept C8891405 @default.
• W1568573049 hasConcept C94205230 @default.
• W1568573049 hasConcept C95444343 @default.
• W1568573049 hasConcept C96926380 @default.
• W1568573049 hasConceptScore W1568573049C12823836 @default.
• W1568573049 hasConceptScore W1568573049C13373296 @default.
• W1568573049 hasConceptScore W1568573049C147483822 @default.
• W1568573049 hasConceptScore W1568573049C159654299 @default.
• W1568573049 hasConceptScore W1568573049C200180986 @default.
• W1568573049 hasConceptScore W1568573049C203014093 @default.
• W1568573049 hasConceptScore W1568573049C2776090121 @default.
• W1568573049 hasConceptScore W1568573049C2776914184 @default.
• W1568573049 hasConceptScore W1568573049C2778453870 @default.
• W1568573049 hasConceptScore W1568573049C2778957590 @default.
• W1568573049 hasConceptScore W1568573049C67662055 @default.
• W1568573049 hasConceptScore W1568573049C83360876 @default.
• W1568573049 hasConceptScore W1568573049C86803240 @default.
• W1568573049 hasConceptScore W1568573049C8891405 @default.
• W1568573049 hasConceptScore W1568573049C94205230 @default.
• W1568573049 hasConceptScore W1568573049C95444343 @default.

• next