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- W156861360 abstract "Retrolental fibroplasia (RLF) was first described in 1942 by Terry (1942), as a condition which developed after birth initially thought to be due to the persistence of the entire vascular structure of the fetal vitreous. The term “retrolental fibroplasia” was apparently coined by a Boston opthalmologist, Doctor H. Messenger (Silverman, 1980) and by the 1950’s RLF was thought to be the commonest cause of infant blindness. Following Terry’s original description of RLF this condition began to be reported with increasing frequency occurring in approximately 12% of infants of less than 1400 gm in the late 1940s (Terry, 1945). The temporal changes in the retina of premature infants with RLF was first detailed by Owens & Owens of the Wilmer Eye Institute at Johns Hopkins Hospital (Owens & Owens) who described the first abnormalities as the dilation of veins, following which the arteries became dilated and tortuous. Subsequently new vessel formation was observed and was followed by retinal edema and hemorrhages. Pathologic studies demonstrated that the primary lesion was a disordered capillary endothelial proliferation within the retina which was associated with pre-retinal and vitreous hemorrhages, and fibrotic changes (Friedenwald, 1951). I have retained the term RLF as opposed to the the more recently accepted retinopathy of prematurity (ROP) because RLF was the term used in the great majority of cited papers. RLF more accurately refers to the cicatricial grades of the disorder whereas ROP has a broader connotation." @default.
- W156861360 created "2016-06-24" @default.
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- W156861360 date "1987-01-01" @default.
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- W156861360 title "Current Status of Vitamin E in Retinopathy of Prematurity" @default.
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- W156861360 doi "https://doi.org/10.1007/978-1-4612-4784-5_10" @default.
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