Matches in SemOpenAlex for { <https://semopenalex.org/work/W1568852071> ?p ?o ?g. }
- W1568852071 endingPage "17061" @default.
- W1568852071 startingPage "17056" @default.
- W1568852071 abstract "Binding of fibroblast growth factor (FGF) to the fibroblast growth factor receptor leads to autophosphorylation of the receptor on several tyrosine residues. Wild-type FGF receptor 1 (flg) and a mutated receptor (Y766F), in which an autophosphorylation site (Tyr-766) was mutated to phenylalanine, were expressed in rat myoblasts and in hematopoietic Ba/F3 cells. It was found that the point mutation at Tyr-766 resulted in a decrease in FGF receptor internalization, as well as a reduction in both ligand-induced FGF receptor down-regulation and degradation. It has been shown previously that phosphorylation of Tyr-766 is essential for interaction with phospholipase C gamma and that the Y766F FGF receptor mutant is unable to stimulate phosphatidylinositol hydrolysis and Ca2+ release from internal stores. The results presented in this report indicate that Tyr-766 is also essential for cellular trafficking of FGF receptor." @default.
- W1568852071 created "2016-06-24" @default.
- W1568852071 creator A5064779039 @default.
- W1568852071 creator A5067994300 @default.
- W1568852071 creator A5086865661 @default.
- W1568852071 creator A5088912114 @default.
- W1568852071 date "1994-06-01" @default.
- W1568852071 modified "2023-10-13" @default.
- W1568852071 title "Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766." @default.
- W1568852071 cites W105106768 @default.
- W1568852071 cites W1191078096 @default.
- W1568852071 cites W1483159812 @default.
- W1568852071 cites W1487627529 @default.
- W1568852071 cites W1489118721 @default.
- W1568852071 cites W1513625834 @default.
- W1568852071 cites W1529444545 @default.
- W1568852071 cites W1531144136 @default.
- W1568852071 cites W1592646667 @default.
- W1568852071 cites W1608794391 @default.
- W1568852071 cites W166089919 @default.
- W1568852071 cites W1854803455 @default.
- W1568852071 cites W1961999388 @default.
- W1568852071 cites W1969642134 @default.
- W1568852071 cites W1972960760 @default.
- W1568852071 cites W1974199993 @default.
- W1568852071 cites W1974873948 @default.
- W1568852071 cites W1979403186 @default.
- W1568852071 cites W1985457327 @default.
- W1568852071 cites W1990494772 @default.
- W1568852071 cites W1992628345 @default.
- W1568852071 cites W1992894005 @default.
- W1568852071 cites W1995574514 @default.
- W1568852071 cites W2000282041 @default.
- W1568852071 cites W2000894432 @default.
- W1568852071 cites W2004786597 @default.
- W1568852071 cites W2008980811 @default.
- W1568852071 cites W2019626689 @default.
- W1568852071 cites W2021210918 @default.
- W1568852071 cites W2022378877 @default.
- W1568852071 cites W2027667306 @default.
- W1568852071 cites W2032359283 @default.
- W1568852071 cites W2035584408 @default.
- W1568852071 cites W2036895735 @default.
- W1568852071 cites W2037956598 @default.
- W1568852071 cites W2040987875 @default.
- W1568852071 cites W2044075747 @default.
- W1568852071 cites W2055473408 @default.
- W1568852071 cites W2055963067 @default.
- W1568852071 cites W2073195662 @default.
- W1568852071 cites W2076606225 @default.
- W1568852071 cites W2077687566 @default.
- W1568852071 cites W2084285799 @default.
- W1568852071 cites W2088775512 @default.
- W1568852071 cites W2094340094 @default.
- W1568852071 cites W2099543104 @default.
- W1568852071 cites W2107245671 @default.
- W1568852071 cites W2108264768 @default.
- W1568852071 cites W2113266466 @default.
- W1568852071 cites W2119561579 @default.
- W1568852071 cites W2122225748 @default.
- W1568852071 cites W2138466097 @default.
- W1568852071 cites W2156153189 @default.
- W1568852071 cites W2175146729 @default.
- W1568852071 cites W2199620244 @default.
- W1568852071 cites W4245704991 @default.
- W1568852071 cites W4255042798 @default.
- W1568852071 cites W67169912 @default.
- W1568852071 doi "https://doi.org/10.1016/s0021-9258(17)32519-x" @default.
- W1568852071 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7516330" @default.
- W1568852071 hasPublicationYear "1994" @default.
- W1568852071 type Work @default.
- W1568852071 sameAs 1568852071 @default.
- W1568852071 citedByCount "114" @default.
- W1568852071 countsByYear W15688520712012 @default.
- W1568852071 countsByYear W15688520712013 @default.
- W1568852071 countsByYear W15688520712014 @default.
- W1568852071 countsByYear W15688520712015 @default.
- W1568852071 countsByYear W15688520712016 @default.
- W1568852071 countsByYear W15688520712017 @default.
- W1568852071 countsByYear W15688520712018 @default.
- W1568852071 countsByYear W15688520712019 @default.
- W1568852071 countsByYear W15688520712020 @default.
- W1568852071 countsByYear W15688520712021 @default.
- W1568852071 countsByYear W15688520712022 @default.
- W1568852071 countsByYear W15688520712023 @default.
- W1568852071 crossrefType "journal-article" @default.
- W1568852071 hasAuthorship W1568852071A5064779039 @default.
- W1568852071 hasAuthorship W1568852071A5067994300 @default.
- W1568852071 hasAuthorship W1568852071A5086865661 @default.
- W1568852071 hasAuthorship W1568852071A5088912114 @default.
- W1568852071 hasBestOaLocation W15688520711 @default.
- W1568852071 hasConcept C104317684 @default.
- W1568852071 hasConcept C139770010 @default.
- W1568852071 hasConcept C147708747 @default.
- W1568852071 hasConcept C170493617 @default.
- W1568852071 hasConcept C176944494 @default.
- W1568852071 hasConcept C185592680 @default.
- W1568852071 hasConcept C2776165026 @default.