FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1569018409> ?p ?o ?g. }

• W1569018409 endingPage "10425" @default.
• W1569018409 startingPage "10422" @default.
• W1569018409 abstract "The control of isocitrate dehydrogenase through phosphorylation is necessary for growth of Escherichia coli on acetate as the sole carbon source. To understand the mechanism by which phosphorylation inactivates isocitrate dehydrogenase, the sequence of icd, the isocitrate dehydrogenase structural gene, was determined and this information was used to construct mutants at the site of phosphorylation. Introduction of a negatively charged aspartate for the serine that is phosphorylated completely inactivates isocitrate dehydrogenase. Substitution of the serine with other amino acids results in a partially active enzyme in which both maximal velocity and interaction with substrates has been altered. Neither threonine nor tyrosine, when substituted for the serine at the phosphorylation site, is detectably phosphorylated by isocitrate dehydrogenase kinase." @default.
• W1569018409 created "2016-06-24" @default.
• W1569018409 creator A5005405478 @default.
• W1569018409 creator A5076791930 @default.
• W1569018409 date "1987-08-01" @default.
• W1569018409 modified "2023-10-16" @default.
• W1569018409 title "Inactivation of isocitrate dehydrogenase by phosphorylation is mediated by the negative charge of the phosphate." @default.
• W1569018409 cites W1490238718 @default.
• W1569018409 cites W1496388590 @default.
• W1569018409 cites W1555898673 @default.
• W1569018409 cites W1559617413 @default.
• W1569018409 cites W1563853646 @default.
• W1569018409 cites W1594677530 @default.
• W1569018409 cites W1775749144 @default.
• W1569018409 cites W1781531090 @default.
• W1569018409 cites W1992472345 @default.
• W1569018409 cites W2001769819 @default.
• W1569018409 cites W2008936546 @default.
• W1569018409 cites W2021963261 @default.
• W1569018409 cites W2028701325 @default.
• W1569018409 cites W2029195137 @default.
• W1569018409 cites W2030349770 @default.
• W1569018409 cites W2030648948 @default.
• W1569018409 cites W2032462421 @default.
• W1569018409 cites W2036931150 @default.
• W1569018409 cites W2044973253 @default.
• W1569018409 cites W2048053624 @default.
• W1569018409 cites W2049031189 @default.
• W1569018409 cites W2059890422 @default.
• W1569018409 cites W2061202598 @default.
• W1569018409 cites W2083963451 @default.
• W1569018409 cites W2138270253 @default.
• W1569018409 cites W986789882 @default.
• W1569018409 doi "https://doi.org/10.1016/s0021-9258(18)60975-5" @default.
• W1569018409 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3112144" @default.
• W1569018409 hasPublicationYear "1987" @default.
• W1569018409 type Work @default.
• W1569018409 sameAs 1569018409 @default.
• W1569018409 citedByCount "279" @default.
• W1569018409 countsByYear W15690184092012 @default.
• W1569018409 countsByYear W15690184092013 @default.
• W1569018409 countsByYear W15690184092014 @default.
• W1569018409 countsByYear W15690184092015 @default.
• W1569018409 countsByYear W15690184092016 @default.
• W1569018409 countsByYear W15690184092017 @default.
• W1569018409 countsByYear W15690184092018 @default.
• W1569018409 countsByYear W15690184092019 @default.
• W1569018409 countsByYear W15690184092020 @default.
• W1569018409 countsByYear W15690184092021 @default.
• W1569018409 countsByYear W15690184092022 @default.
• W1569018409 countsByYear W15690184092023 @default.
• W1569018409 crossrefType "journal-article" @default.
• W1569018409 hasAuthorship W1569018409A5005405478 @default.
• W1569018409 hasAuthorship W1569018409A5076791930 @default.
• W1569018409 hasBestOaLocation W15690184091 @default.
• W1569018409 hasConcept C104317684 @default.
• W1569018409 hasConcept C11960822 @default.
• W1569018409 hasConcept C121332964 @default.
• W1569018409 hasConcept C127848430 @default.
• W1569018409 hasConcept C181199279 @default.
• W1569018409 hasConcept C185592680 @default.
• W1569018409 hasConcept C188082385 @default.
• W1569018409 hasConcept C2776317432 @default.
• W1569018409 hasConcept C2777132085 @default.
• W1569018409 hasConcept C2777150147 @default.
• W1569018409 hasConcept C501734568 @default.
• W1569018409 hasConcept C55493867 @default.
• W1569018409 hasConcept C62520636 @default.
• W1569018409 hasConceptScore W1569018409C104317684 @default.
• W1569018409 hasConceptScore W1569018409C11960822 @default.
• W1569018409 hasConceptScore W1569018409C121332964 @default.
• W1569018409 hasConceptScore W1569018409C127848430 @default.
• W1569018409 hasConceptScore W1569018409C181199279 @default.
• W1569018409 hasConceptScore W1569018409C185592680 @default.
• W1569018409 hasConceptScore W1569018409C188082385 @default.
• W1569018409 hasConceptScore W1569018409C2776317432 @default.
• W1569018409 hasConceptScore W1569018409C2777132085 @default.
• W1569018409 hasConceptScore W1569018409C2777150147 @default.
• W1569018409 hasConceptScore W1569018409C501734568 @default.
• W1569018409 hasConceptScore W1569018409C55493867 @default.
• W1569018409 hasConceptScore W1569018409C62520636 @default.
• W1569018409 hasIssue "22" @default.
• W1569018409 hasLocation W15690184091 @default.
• W1569018409 hasOpenAccess W1569018409 @default.
• W1569018409 hasPrimaryLocation W15690184091 @default.
• W1569018409 hasRelatedWork W1557898514 @default.
• W1569018409 hasRelatedWork W1824539338 @default.
• W1569018409 hasRelatedWork W1964249184 @default.
• W1569018409 hasRelatedWork W2008227564 @default.
• W1569018409 hasRelatedWork W2069303197 @default.
• W1569018409 hasRelatedWork W2084945856 @default.
• W1569018409 hasRelatedWork W2146742335 @default.
• W1569018409 hasRelatedWork W2170206357 @default.
• W1569018409 hasRelatedWork W2353247773 @default.
• W1569018409 hasRelatedWork W3185195364 @default.
• W1569018409 hasVolume "262" @default.
• W1569018409 isParatext "false" @default.
• W1569018409 isRetracted "false" @default.

• next