Matches in SemOpenAlex for { <https://semopenalex.org/work/W1569062815> ?p ?o ?g. }
- W1569062815 endingPage "460" @default.
- W1569062815 startingPage "450" @default.
- W1569062815 abstract "The plasminogen activator liberated by cells of human neuroblastoma strain SK-N-SH was purified up to 400-fold, with a 40% recovery of activity, by a relatively simple procedure. This involved (NH4)2SO4 precipitation, followed by chromatography on both Affi-Gel Blue and p-aminobenzaminidine-Sepharose. The SK-N-SH activator was shown to differ from human urokinase with respect to immunological specificity, the molecular weights and isoelectric points of their enzymatically active species, the ability to be activated by fibrin and their relative sensitivities to inactivation by diisopropyl fluorophosphate. The average molecular weights of the enzymatically active species derived from strain SK-N-SH were shown to be 66,500, 64,500, 60,500 and 37,500. In the presence of fibrin, the SK-N-SH plasminogen activator appeared to be stimulated approximately 16-fold, with no apparent stimulation of urokinase activity. Urokinase is inactivated by diisopropyl fluorophosphate at a rate 6.4-fold faster than that of the SK-N-SH activator." @default.
- W1569062815 created "2016-06-24" @default.
- W1569062815 creator A5060540696 @default.
- W1569062815 creator A5060854283 @default.
- W1569062815 date "1982-06-01" @default.
- W1569062815 modified "2023-10-14" @default.
- W1569062815 title "Characterization and partial purification of the plasminogen activator from human neuroblastoma cell line, SK-N-SH" @default.
- W1569062815 cites W104868848 @default.
- W1569062815 cites W1515213049 @default.
- W1569062815 cites W1540618467 @default.
- W1569062815 cites W1585742295 @default.
- W1569062815 cites W1598110035 @default.
- W1569062815 cites W1606423922 @default.
- W1569062815 cites W1973413312 @default.
- W1569062815 cites W1976180883 @default.
- W1569062815 cites W1976359283 @default.
- W1569062815 cites W1978114500 @default.
- W1569062815 cites W1985479817 @default.
- W1569062815 cites W1987233669 @default.
- W1569062815 cites W1989861077 @default.
- W1569062815 cites W1996636157 @default.
- W1569062815 cites W2000429229 @default.
- W1569062815 cites W2003866166 @default.
- W1569062815 cites W2013393649 @default.
- W1569062815 cites W2022246724 @default.
- W1569062815 cites W2027791916 @default.
- W1569062815 cites W2035989734 @default.
- W1569062815 cites W2042786025 @default.
- W1569062815 cites W2047577088 @default.
- W1569062815 cites W2053192974 @default.
- W1569062815 cites W2053808100 @default.
- W1569062815 cites W2059989570 @default.
- W1569062815 cites W2065423329 @default.
- W1569062815 cites W2069843332 @default.
- W1569062815 cites W2073879684 @default.
- W1569062815 cites W2074809813 @default.
- W1569062815 cites W2082493157 @default.
- W1569062815 cites W2087429238 @default.
- W1569062815 cites W2090191865 @default.
- W1569062815 cites W2100837269 @default.
- W1569062815 cites W2104886744 @default.
- W1569062815 cites W2122094046 @default.
- W1569062815 cites W2164358316 @default.
- W1569062815 cites W2206615847 @default.
- W1569062815 cites W2281307694 @default.
- W1569062815 cites W2408510909 @default.
- W1569062815 cites W2410592017 @default.
- W1569062815 doi "https://doi.org/10.1016/0167-4838(82)90067-x" @default.
- W1569062815 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7052133" @default.
- W1569062815 hasPublicationYear "1982" @default.
- W1569062815 type Work @default.
- W1569062815 sameAs 1569062815 @default.
- W1569062815 citedByCount "15" @default.
- W1569062815 countsByYear W15690628152013 @default.
- W1569062815 countsByYear W15690628152016 @default.
- W1569062815 countsByYear W15690628152017 @default.
- W1569062815 countsByYear W15690628152023 @default.
- W1569062815 crossrefType "journal-article" @default.
- W1569062815 hasAuthorship W1569062815A5060540696 @default.
- W1569062815 hasAuthorship W1569062815A5060854283 @default.
- W1569062815 hasConcept C134018914 @default.
- W1569062815 hasConcept C153911025 @default.
- W1569062815 hasConcept C170493617 @default.
- W1569062815 hasConcept C179247698 @default.
- W1569062815 hasConcept C181199279 @default.
- W1569062815 hasConcept C185592680 @default.
- W1569062815 hasConcept C203014093 @default.
- W1569062815 hasConcept C2776873056 @default.
- W1569062815 hasConcept C2776892390 @default.
- W1569062815 hasConcept C2779679481 @default.
- W1569062815 hasConcept C2779881004 @default.
- W1569062815 hasConcept C2781071845 @default.
- W1569062815 hasConcept C43617362 @default.
- W1569062815 hasConcept C50476208 @default.
- W1569062815 hasConcept C54173615 @default.
- W1569062815 hasConcept C54355233 @default.
- W1569062815 hasConcept C55493867 @default.
- W1569062815 hasConcept C86803240 @default.
- W1569062815 hasConcept C88045685 @default.
- W1569062815 hasConcept C96294017 @default.
- W1569062815 hasConceptScore W1569062815C134018914 @default.
- W1569062815 hasConceptScore W1569062815C153911025 @default.
- W1569062815 hasConceptScore W1569062815C170493617 @default.
- W1569062815 hasConceptScore W1569062815C179247698 @default.
- W1569062815 hasConceptScore W1569062815C181199279 @default.
- W1569062815 hasConceptScore W1569062815C185592680 @default.
- W1569062815 hasConceptScore W1569062815C203014093 @default.
- W1569062815 hasConceptScore W1569062815C2776873056 @default.
- W1569062815 hasConceptScore W1569062815C2776892390 @default.
- W1569062815 hasConceptScore W1569062815C2779679481 @default.
- W1569062815 hasConceptScore W1569062815C2779881004 @default.
- W1569062815 hasConceptScore W1569062815C2781071845 @default.
- W1569062815 hasConceptScore W1569062815C43617362 @default.
- W1569062815 hasConceptScore W1569062815C50476208 @default.
- W1569062815 hasConceptScore W1569062815C54173615 @default.
- W1569062815 hasConceptScore W1569062815C54355233 @default.
- W1569062815 hasConceptScore W1569062815C55493867 @default.
- W1569062815 hasConceptScore W1569062815C86803240 @default.