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• W1569108431 startingPage "467" @default.
• W1569108431 abstract "Vasopressin (VP) is a peptide neurotransmitter in the limbic system of rats. It is synthesized in the medial amygdaloid nucleus in the presence of sex steroids, transported to other limbic structures such as the hippocampus and septum and secreted there by a calcium-dependent process. In the hippocampus, VP acts on cerebral microvessels and local circuit interneurons. Its excitatory action on the inhibitory interneurons produces near-total shutdown of electrical activity of the efferent fibers of pyramidal cells, the projection neurons of the hippocampus. Stimulation of the medial amygdala and release of the endogenous VP duplicates these effects and, since they are blocked by ventricular application of a VP antagonist, the effects are almost certainly mediated by endogenous VP. Recording from the VP-containing cell bodies or of the hippocampal action of the peptide indicates that the system is selectively involved with the early stages of sexual behavior, specifically those appetitive behaviors that anticipate coitus. Stimulation of the VP cells produces alterations in sexual behavior in a manner consistent with the hypothesis that the medial amygdala organizes the appetitive phase of recognition of an appropriate partner and sexual arousal. This role for the medial amygdala complements the proposed role of nearby structures in the consummatory, reward and learned aspects of sexual behavior. Association between VP, oxytocin (OT) and homologs with sexual behavior is very widespread among vertebrates, including amphibians, reptiles, primates and humans. Humans and other primates display a phenomenon called 'concealed ovulation' that may have played a role in the evolution of social structures. The review concludes with a discussion of possible experimental strategies for evaluating the possible role of VP in concealed ovulation and other conditions in which sexual behavior occurs outside of estrus." @default.
• W1569108431 created "2016-06-24" @default.
• W1569108431 creator A5012352308 @default.
• W1569108431 creator A5027897843 @default.
• W1569108431 creator A5077476110 @default.
• W1569108431 date "1999-01-01" @default.
• W1569108431 modified "2023-10-10" @default.
• W1569108431 title "A peptidergic basis for sexual behavior in mammals" @default.
• W1569108431 cites W1591828201 @default.
• W1569108431 cites W1960686950 @default.
• W1569108431 cites W1971593578 @default.
• W1569108431 cites W1974040746 @default.
• W1569108431 cites W1974090890 @default.
• W1569108431 cites W1974318670 @default.
• W1569108431 cites W1975239248 @default.
• W1569108431 cites W1975533030 @default.
• W1569108431 cites W1982108627 @default.
• W1569108431 cites W1983817994 @default.
• W1569108431 cites W1983894234 @default.
• W1569108431 cites W1989064357 @default.
• W1569108431 cites W1991042183 @default.
• W1569108431 cites W1991172664 @default.
• W1569108431 cites W1993731512 @default.
• W1569108431 cites W1993786759 @default.
• W1569108431 cites W1994819089 @default.
• W1569108431 cites W1996047916 @default.
• W1569108431 cites W1997819092 @default.
• W1569108431 cites W1998689277 @default.
• W1569108431 cites W2001158115 @default.
• W1569108431 cites W2003310545 @default.
• W1569108431 cites W2006189845 @default.
• W1569108431 cites W2010262150 @default.
• W1569108431 cites W2010624346 @default.
• W1569108431 cites W2010711792 @default.
• W1569108431 cites W2011463948 @default.
• W1569108431 cites W2012392333 @default.
• W1569108431 cites W2012578231 @default.
• W1569108431 cites W2013897317 @default.
• W1569108431 cites W2014539594 @default.
• W1569108431 cites W2015421821 @default.
• W1569108431 cites W2022227059 @default.
• W1569108431 cites W2024117628 @default.
• W1569108431 cites W2024296387 @default.
• W1569108431 cites W2027061276 @default.
• W1569108431 cites W2027710787 @default.
• W1569108431 cites W2029009970 @default.
• W1569108431 cites W2030274387 @default.
• W1569108431 cites W2034398442 @default.
• W1569108431 cites W2035261481 @default.
• W1569108431 cites W2037129036 @default.
• W1569108431 cites W2039013426 @default.
• W1569108431 cites W2041680408 @default.
• W1569108431 cites W2043050293 @default.
• W1569108431 cites W2046418079 @default.
• W1569108431 cites W2048950217 @default.
• W1569108431 cites W2049258982 @default.
• W1569108431 cites W2052339877 @default.
• W1569108431 cites W2056144641 @default.
• W1569108431 cites W2057394847 @default.
• W1569108431 cites W2059297425 @default.
• W1569108431 cites W2060119563 @default.
• W1569108431 cites W2060628881 @default.
• W1569108431 cites W2061840967 @default.
• W1569108431 cites W2061875648 @default.
• W1569108431 cites W2066375077 @default.
• W1569108431 cites W2068838328 @default.
• W1569108431 cites W2069085535 @default.
• W1569108431 cites W2069926158 @default.
• W1569108431 cites W2070799851 @default.
• W1569108431 cites W2071308752 @default.
• W1569108431 cites W2072179006 @default.
• W1569108431 cites W2072476900 @default.
• W1569108431 cites W2072868968 @default.
• W1569108431 cites W2073833456 @default.
• W1569108431 cites W2074527323 @default.
• W1569108431 cites W2075171594 @default.
• W1569108431 cites W2075522790 @default.
• W1569108431 cites W2081833081 @default.
• W1569108431 cites W2082133508 @default.
• W1569108431 cites W2085948837 @default.
• W1569108431 cites W2086900822 @default.
• W1569108431 cites W2088205204 @default.
• W1569108431 cites W2090529422 @default.
• W1569108431 cites W2092863206 @default.
• W1569108431 cites W2093880793 @default.
• W1569108431 cites W2095110487 @default.
• W1569108431 cites W2095379210 @default.
• W1569108431 cites W2098003814 @default.
• W1569108431 cites W2104832253 @default.
• W1569108431 cites W2113034057 @default.
• W1569108431 cites W2119627796 @default.
• W1569108431 cites W2121061650 @default.
• W1569108431 cites W2128628605 @default.
• W1569108431 cites W2131580854 @default.
• W1569108431 cites W2134262490 @default.
• W1569108431 cites W2135397106 @default.
• W1569108431 cites W2139623582 @default.
• W1569108431 cites W2140288223 @default.

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