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- W1569191725 abstract "Penicillinase-producing strains of Staphylococcus aureus are transformed into stable L colonies by 70 to 100 subcultures on methicillin-containing medium with a suitable high osmolarity. During transformation, the penicillinase activity is lost. This loss in activity is not the result of only the penicillinase-negative mutants transforming to L colonies. If unstable L colonies are filtered through 0.45-μm membrane filters immediately after transformation, still no penicillinase activity is seen; this is also the case if the filtrated L colonies are reverted into coccal forms. The mechanism responsible for the loss of penicillinase activity is discussed. A loss of the penicillinase plasmid is proposed as the most reasonable explanation." @default.
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- W1569191725 date "1970-12-01" @default.
- W1569191725 modified "2023-09-27" @default.
- W1569191725 title "Investigation of the Penicillinase Activity in L Colonies of Staphylococcus aureus" @default.
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- W1569191725 doi "https://doi.org/10.1128/am.20.6.871-874.1970" @default.
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