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- W1569207981 abstract "A study on the identification of hybrids identified six distinct clusters based on the genotypes of a large number of Cryptococcus neoformans and Cryptococcus gattii global isolates using amplified fragment length polymorphism (AFLP). A combination of genotype and ploidy analyses are able to discriminate AD hybrids from haploid serotype A or D isolates. Serological reactions and a set of genotyping techniques have been used to determine the serotype of Cryptococcus strains. Serotype A strains presented a rim pattern characterized by a sharp increase in the optical gradient at the capsular edge followed directly by an immediate decrease. The estimation of the time of hybridization showed that recombination occurred very recently, indicating that hybridization is important during Cryptococcus evolution. Gene genealogical analysis supported the hypothesis of multiple origins of hybrid strains, suggesting that hybridization events occurred in different times probably coinciding with the continuing dispersion of C. neoformans in the environment that allows the contact between genetic divergent populations. In conclusion, hybridization, in addition to a low rate of sexual reproduction, represents an important mechanism for Cryptococcus to introduce genetic variants in a population with a prevalent clonal expansion." @default.
- W1569207981 created "2016-06-24" @default.
- W1569207981 creator A5014740040 @default.
- W1569207981 creator A5022829371 @default.
- W1569207981 creator A5090442574 @default.
- W1569207981 date "2014-04-09" @default.
- W1569207981 modified "2023-10-16" @default.
- W1569207981 title "Hybridization and Its Importance in the<i>Cryptococcus</i>Species Complex" @default.
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- W1569207981 doi "https://doi.org/10.1128/9781555816858.ch25" @default.
- W1569207981 hasPublicationYear "2014" @default.
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